Clinical Effectiveness of Two Old Immunosuppressant Drugs, Methotrexate and Azathioprine, in the Treatment of Lichen Planopilaris: A Randomized Clinical Trial

    January 2024 in “ Dermatologic Therapy ”
    Mina Saber, Parisa Hajheidari, Farahnaz Fatemi Naeini, Fatemeh Mohaghegh
    Studysummary This study found that both methotrexate and azathioprine were equally effective and well-tolerated in improving symptoms of lichen planopilaris over six months, with no significant difference between the two treatments in terms of efficacy.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on onlinelibrary.wiley.com →
    Discuss this study in the Community →

    Research cited in this study 10

    1. A Systematic Review And Bayesian Network Meta-Analysis Of Medical Therapies For Lichen Planopilaris Dermatology · 2023
    2. Clinical Effectiveness of Finasteride Versus Hydroxychloroquine in the Treatment of Frontal Fibrosing Alopecia: A Randomized Controlled Trial Journal of Cosmetic Dermatology · 2023
    3. Comparative Efficacy Study of Combination of Oral Methotrexate and Prednisolone Versus Oral Methotrexate in Patients with Lichen Planopilaris Dermatology Research and Practice · 2022
    4. Lichen Planopilaris: Retrospective Study on the Characteristics and Treatment of 291 Patients Journal of dermatological treatment · 2018
    5. Comparison of Systemic Mycophenolate Mofetil with Topical Clobetasol in Lichen Planopilaris: A Parallel-Group, Assessor- and Analyst-Blinded, Randomized Controlled Trial American journal of clinical dermatology · 2015
    6. Primary Cicatricial Alopecia: Diagnosis and Treatment Canadian Medical Association Journal · 2013
    7. Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review Journal of the European Academy of Dermatology and Venereology · 2013
    8. Commentary: Treatment of Lichen Planopilaris Journal of The American Academy of Dermatology · 2010
    9. Lichen Planopilaris: Update on Diagnosis and Treatment Seminars in Cutaneous Medicine and Surgery · 2009
    10. Lichen Planopilaris: Chronic Scarring Alopecia with Autoimmune Component Dermatologic therapy · 2008