Systemic Treatments for Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective Study of 315 Patients

    April 2025 in “ Acta Dermato Venereologica ”
    Mathias Willaert, Tristan Van Dongen, Petra Dikrama … Rick Waalboer‐Spuij
    Studysummary In this study, a retrospective analysis at Erasmus University Medical Center found that methotrexate and cyclosporine A may be most effective for lichen planopilaris and cyclosporine A and retinoids for frontal fibrosing alopecia, although side effects were a concern.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on medicaljournalssweden.se →
    Discuss this study in the Community →

    Research cited in this study 18

    1. Lichen Planopilaris and Frontal Fibrosing Alopecia: Review and Update of Diagnostic and Therapeutic Features Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia · 2022
    2. Differentiation of Frontal Fibrosing Alopecia and Lichen Planopilaris on Trichoscopy: A Comprehensive Review Journal of Cosmetic Dermatology · 2021
    3. Lichen Planopilaris in Men: A Retrospective Clinicopathologic Study of 19 Patients International Journal of Dermatology · 2020
    4. PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology Experimental Dermatology · 2019
    5. Frontal Fibrosing Alopecia in Asians: A Retrospective Clinical Study International Journal of Dermatology · 2019
    6. Medical Therapy for Frontal Fibrosing Alopecia: A Review and Clinical Approach Journal of The American Academy of Dermatology · 2019
    7. Frontal Fibrosing Alopecia: Efficacy of Treatment Modalities International Journal of Women's Health · 2019
    8. Frontal Fibrosing Alopecia: An Update on Pathogenesis, Diagnosis, and Treatment American Journal of Clinical Dermatology · 2019
    9. Lichen Planopilaris: Retrospective Study on the Characteristics and Treatment of 291 Patients Journal of dermatological treatment · 2018
    10. Cicatricial Alopecia: Overview and Treatment Recommendations Journal der Deutschen Dermatologischen Gesellschaft · 2018
    11. Therapeutic management of classic lichen planopilaris: a systematic review Clinical Cosmetic and Investigational Dermatology · 2018
    12. PPAR-γ Agonists and Their Role in Primary Cicatricial Alopecia PPAR Research · 2017
    13. Lichen Planopilaris Epidemiology: A Retrospective Study of 80 Cases Anais Brasileiros de Dermatologia · 2015
    14. A Case Series of 46 Patients With Lichen Planopilaris: Demographics, Clinical Evaluation, and Treatment Experience Journal of Dermatological Treatment · 2014
    15. Primary Cicatricial Alopecia: Diagnosis and Treatment Canadian Medical Association Journal · 2013
    16. Treatment of Frontal Fibrosing Alopecia and Lichen Planopilaris: A Systematic Review Journal of the European Academy of Dermatology and Venereology · 2013
    17. Cicatricial (Scarring) Alopecias: Comprehensive Review and Management American Journal of Clinical Dermatology · 2012
    18. The Pathogenesis of Primary Cicatricial Alopecias The American Journal of Pathology · 2010

    Related research 8

    1. Bitemporal Scalp Hair Loss: Differential Diagnosis of Nonscarring and Scarring Conditions The Journal of clinical and aesthetic dermatology · 2021
    2. Gynecologic and Hormonal Comorbidities of Scarring Alopecia: A Retrospective Review Journal of Investigative Dermatology · 2019
    3. The Diagnosis and Treatment of Hair and Scalp Diseases Deutsches Arzteblatt International · 2016
    4. Acquired Alopecia In Childhood Der Hautarzt · 2013
    5. Break Dancing: A New Risk Factor for Scarring Hair Loss Journal of Cutaneous Medicine and Surgery · 2011
    6. Hair Diseases Medical Clinics of North America · 1998
    7. Evaluation of Hair Loss Current problems in dermatology · 1996
    8. Androgenetic Alopecia, Trichotrophic Substances, and Histologic Studies of the Human Scalp Clinics in Dermatology · 1988