Comparative Efficacy Study of Combination of Oral Methotrexate and Prednisolone Versus Oral Methotrexate in Patients with Lichen Planopilaris

    January 2022 in “ Dermatology Research and Practice ”
    Farahnaz Fatemi Naeini, Farifteh Esfahanian, Ali Asilian … Mina Saber
    Studysummary In this study, methotrexate therapy with or without corticosteroids showed similar efficacy and safety in treating patients with lichen planopilaris, with no significant differences in the primary outcome or adverse effects between the two groups.
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    Research cited in this study 11

    1. Lichen Planopilaris Epidemiology: A Retrospective Study of 80 Cases Anais Brasileiros de Dermatologia · 2015
    2. Comparison of Systemic Mycophenolate Mofetil with Topical Clobetasol in Lichen Planopilaris: A Parallel-Group, Assessor- and Analyst-Blinded, Randomized Controlled Trial American journal of clinical dermatology · 2015
    3. A Case Series of 46 Patients With Lichen Planopilaris: Demographics, Clinical Evaluation, and Treatment Experience Journal of Dermatological Treatment · 2014
    4. Frontal Fibrosing Alopecia: A Review of 60 Cases Journal of The American Academy of Dermatology · 2012
    5. Global Photographic Assessment of Men Aged 18 to 60 Years with Male Pattern Hair Loss Receiving Finasteride 1 mg or Placebo Journal of The American Academy of Dermatology · 2012
    6. Efficacy and Safety of Mycophenolate Mofetil for Lichen Planopilaris Journal of The American Academy of Dermatology · 2010
    7. Lichen Planopilaris Treated With a Peroxisome Proliferator-Activated Receptor Gamma Agonist Archives of dermatology · 2009
    8. Lichen Planopilaris: Update on Diagnosis and Treatment Seminars in Cutaneous Medicine and Surgery · 2009
    9. A Histologic Review of 27 Patients with Lichen Planopilaris Journal of the American Academy of Dermatology · 2008
    10. A Case-Series of 29 Patients with Lichen Planopilaris: The Cleveland Clinic Foundation Experience on Evaluation, Diagnosis, and Treatment Journal of the American Academy of Dermatology · 2007
    11. Primary Cicatricial Alopecias: Clinicopathology of 112 Cases Journal of the American Academy of Dermatology · 2003