Combined Minoxidil and Platelet-Rich Plasma Compared With Monotherapy in Androgenetic Alopecia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

September 2025 in “ Journal of the American Academy of Dermatology ”

Nathália Borba, Isabelle Reis, Regiane Lopes de Sales, Beatriz Mendes, Gabrielle Henrique, L.A.R. da Rosa, Risciela Salardi Alves de Brito, Thaís Pincelli

minoxidil platelet-rich plasma androgenetic alopecia randomized controlled trials Rogaine PRP AGA

TLDR Combining minoxidil and PRP is more effective for hair growth than using either alone.

This systematic review and meta-analysis evaluated the effectiveness of combined minoxidil and platelet-rich plasma (PRP) therapy compared to monotherapy in treating androgenetic alopecia (AGA). The study synthesized data from multiple randomized controlled trials to assess the efficacy of these treatments. The findings suggest that the combination of minoxidil and PRP is more effective in promoting hair growth than either treatment alone. This conclusion is based on the analysis of several trials, although the exact number of participants involved in the study is not specified in the provided text. The results support the use of combination therapy as a superior option for individuals suffering from AGA.

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