This study concluded that adding a topical agent to intense pulsed light therapy significantly improved hair reduction and patient satisfaction in Pakistani women with idiopathic facial hirsutism compared to light therapy alone, without increasing adverse effects.
August 2025 in “Indian Dermatology Online Journal” In this study, both methotrexate gel and betamethasone lotion were found to be effective and safe treatments for localized alopecia areata, with similar overall response rates. However, methotrexate gel had a higher incidence of local side effects, such as irritant dermatitis and itching.
August 2025 in “Indian Dermatology Online Journal” This study found that combining topical minoxidil with phototherapy significantly improved pigmentation and reduced vitiligo severity compared to placebo, as measured by VASI scores over 12 weeks, though the sample size was small and follow-up short.
August 2025 in “Nutrients” This Mendelian randomization study found that specific dietary patterns, such as consuming antioxidant-rich foods like melon and tea, may have protective effects against hair loss, while processed carbohydrates, alcohol, and certain dairy products could increase the risk of androgenetic alopecia and alopecia areata.
This phase II study found that a 0.05% topical dutasteride solution was more effective than oral finasteride (1 mg/day) in increasing hair count and width in males with androgenetic alopecia over 24 weeks, without causing irritation.
In this clinical trial, the researchers observed that a biotin and silica supplement reduced hair fall, increased hair growth rate, and improved skin elasticity, hydration, and nail quality over 90 days without adverse effects.
July 2025 in “Journal of Cosmetic Dermatology” In this clinical study involving individuals with localized alopecia areata, TrA injections were found to significantly outperform MTX, leading to better hair regrowth and higher patient satisfaction, though both treatments had similar mild side effects.
July 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found a bidirectional causal association between major depression disorder and alopecia areata, but no association between mental disorders and androgenetic alopecia, suggesting a focus on mental health strategies for alopecia areata management.
June 2025 in “British Journal of Dermatology” This study compared oral tofacitinib and methotrexate in treating moderate-to-severe alopecia areata, finding that tofacitinib was more effective at reducing SALT scores and improving scalp hair assessment PRO scores, though both treatments reduced psychological distress similarly without serious adverse effects.
June 2025 in “British Journal of Dermatology” This study found that both tofacitinib and methotrexate effectively reduced hair loss and psychological distress in patients with moderate-to-severe alopecia areata, but tofacitinib showed much greater efficacy. Both treatments had similar safety profiles, with no serious adverse effects reported.
June 2025 in “Skin Research and Technology” The study's findings on omega-6 and hair loss are unreliable.
This study identified specific gut bacterial pathways that may serve as potential therapeutic targets for managing androgenetic alopecia in obese individuals.
May 2025 in “Actas Dermo-Sifiliográficas” The study did not find evidence to support using botulinum toxin as a treatment for androgenetic alopecia.
May 2025 in “Annals of surgical case reports & images.” Certain gut bacteria may protect against hair loss, while others may increase the risk.
This study found that a novel pet food formulation significantly improved the management of feline atopic skin syndrome by reducing symptom severity and medication dependence over six months in client-owned cats, compared to a control diet.
This study found that oral cyclosporine therapy was more effective than betamethasone mini-pulse therapy for treating alopecia areata, with a better patient-reported outcome on hair regrowth, despite a higher incidence of mild, reversible adverse effects in the cyclosporine group.
May 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This randomized controlled trial found that intralesional vitamin D3 was as effective and safe as intralesional triamcinolone acetonide for treating patchy alopecia areata on the scalp, with no significant influence from serum vitamin D levels on treatment response.
This review discusses the complex causal relationships between testosterone exposure and various health outcomes, but notes that the studies reviewed show substantial heterogeneity.
April 2025 in “Journal of Controversies in Obstetrics & Gynecology and Pediatrics” This study found that vitamin D supplementation significantly improved clinical pregnancy rates in women with polycystic ovary syndrome treated at a Turkish infertility clinic, though it did not affect live birth or miscarriage rates.
April 2025 in “International Journal of Dermatology and Venereology” This study found a significant causal relationship between androgenetic alopecia and schizophrenia, but no causal association between schizophrenia and androgenetic alopecia.
March 2025 in “Chinese Medical Journal” This randomized, double-blind, placebo-controlled phase III trial found that a 24-week treatment with topical finasteride significantly increased hair growth and was well-tolerated in Chinese men with androgenetic alopecia compared to placebo.
February 2025 in “Clinical Cosmetic and Investigational Dermatology” This study used Mendelian randomization analysis to find a significant causal relationship between high fasting insulin levels and androgenetic alopecia, while identifying potential core genes and metabolic pathways that could mediate this link.
February 2025 in “Clinical Cosmetic and Investigational Dermatology” This study suggests that androgenetic alopecia may increase the risk of developing depression, but depression does not significantly contribute to the onset of androgenetic alopecia.
January 2025 in “JAAD International” This randomized, controlled clinical trial found that combining 25 mg/d bicalutamide with 1 mg/d minoxidil for 24 weeks did not enhance hair density improvement in female pattern hair loss compared to 1 mg/d minoxidil alone, with no significant difference observed between the groups.
January 2025 in “Journal of Cosmetic Dermatology” This study suggests that addressing hormonal, stress, and metabolic factors with vitamins, minerals, and botanicals, which has improved hair growth in women, might also benefit men experiencing hair thinning.
November 2024 in “The Journal of Dermatology” This study found that atopic diseases such as atopic dermatitis, asthma, and allergic rhinitis increase the risk of developing alopecia areata, suggesting a significant role for T cell-related inflammation in the condition's mechanism.
November 2024 in “PubMed” Results of the effect and safety of a gummy supplement with B vitamins, zinc, and botanicals on hair growth and quality in women with thinning hair are not reported in this abstract.
September 2024 in “Advanced Biomedical Research” This study compared auriculotherapy, Aslagh capsule, and metformin in women with PCOS, finding auriculotherapy significantly improved menstrual cycle duration and excess hair growth more than the other treatments, though all reduced these symptoms.
August 2024 in “Clinical Cosmetic and Investigational Dermatology” This study investigates the potential causal relationship between hypothyroidism and hair loss conditions like alopecia areata and androgenetic alopecia, noting that previous studies have reported inconsistent findings. Results are not yet detailed.
This study identified four genes related to alopecia areata: GIMAP6 and ALOX15 as risk factors, and GALNT6 and HEG1 as protective factors, noting significant validation differences in GALNT6 and HEG1.