Comparison of the Efficacy of Topical Methotrexate 1% Gel Versus Topical Betamethasone Dipropionate 0.05% Lotion in the Treatment of Localized Scalp Alopecia Areata in a Tertiary Care Institute of Central India: A Randomized Control Trial

    Susmita Banra, Neel Prabha, Soumil Khare
    Studysummary In this study, both methotrexate gel and betamethasone lotion were found to be effective and safe treatments for localized alopecia areata, with similar overall response rates. However, methotrexate gel had a higher incidence of local side effects, such as irritant dermatitis and itching.
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    Research cited in this study 6

    1. Comparative Study Between Topical Methotrexate 1% Gel and Minoxidil 5% Gel in the Treatment of Localized Alopecia Areata Dermatologic Therapy · 2022
    2. A Randomized Comparative Study of the Efficacy of Topical Latanoprost Versus Topical Betamethasone Dipropionate Lotion in the Treatment of Localized Alopecia Areata Indian Journal of Dermatology, Venereology and Leprology · 2021
    3. Alopecia Areata: An Update Indian Journal of Dermatology, Venereology and Leprology · 2013
    4. Alopecia Areata Update Journal of the American Academy of Dermatology · 2010
    5. Alopecia Areata Update Journal of The American Academy of Dermatology · 2010
    6. Efficacy of Betamethasone Valerate Foam Formulation in Comparison with Betamethasone Dipropionate Lotion in the Treatment of Mild-to-Moderate Alopecia Areata: A Multicenter, Prospective, Randomized, Controlled, Investigator-Blinded Trial International Journal of Dermatology · 2003