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Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

New acne treatments show promise as alternatives to traditional therapies.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

About 19.4% of Iranian women in the study have Polycystic Ovary Syndrome, with the most common type involving irregular periods and high male hormone levels, but their heart and metabolic health is similar to women without the condition.

Wet cupping blood has different components than regular venous blood, which might affect skin disorder treatments.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

The study identified 12 potential biomarkers for hair loss and how they affect hair growth.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.

People with hypohidrotic ectodermal dysplasia are more likely to experience long-term fatigue and hair loss after COVID-19.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Metformin, a diabetes drug, may help prevent and treat various cancers, but more research is needed.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Cysteine helps maintain keratin production in skin cells even when iron is low.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Too much androgen can cause hair loss; finasteride may help.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.