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    Did you mean Stem Cell Quiescence?
    Glossary Stem Cell Quiescence

    state where stem cells remain inactive to preserve function

    Stem cell quiescence, also known as stem cell dormancy, refers to a state in which stem cells remain inactive or non-dividing. This state helps protect the stem cells from exhaustion and damage, ensuring they can be activated when needed for tissue repair or regeneration. Quiescent stem cells are crucial for maintaining long-term tissue health and preventing premature aging or diseases like cancer.

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    Research 30 of 1000+

    1. Coexistence of Quiescent and Active Adult Stem Cells in Mammals Science · 2010 · 1201 citations
    2. Quiescent Tissue Stem Cells Evade Immune Surveillance Immunity · 2018 · 169 citations
    3. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018 · 35 citations
    4. Stem Cells on Alert: Priming Quiescent Stem Cells after Remote Injury Cell stem cell · 2014 · 13 citations
    5. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    6. Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing bioRxiv (Cold Spring Harbor Laboratory) · 2023
    7. Molecular heterogeneity of quiescent melanocyte stem cells revealed by single‐cell RNA‐sequencing Pigment cell & melanoma research · 2024
    8. 1438 KLF4 maintains hair follicle stem cell quiescence 2023
    9. Atypical Protein Kinase C Isoform, aPKCλ, Is Essential for Maintaining Hair Follicle Stem Cell Quiescence Journal of Investigative Dermatology · 2015 · 24 citations
    10. The incidental pore: Ca<sub>V</sub>1.2 and stem cell activation in quiescent hair follicles Genes & development · 2013 · 3 citations
    11. The stem cell quiescence and niche signaling is disturbed in the hair follicle of the hairpoor mouse, an MUHH model mouse Stem cell research & therapy · 2022 · 2 citations
    12. The Stem Cell Quiescence and Niche Signaling is Disturbed in the Hair Follicle of the Hairpoor Mouse, an MUHH Model Mouse. Research Square (Research Square) · 2021
    13. A cell polarity protein, aPKCλ, is essential for maintaining hair follicle stem cell quiescence and hair follicle regeneration Journal of Dermatological Science · 2016
    14. Stem cell quiescence acts as a tumour suppressor in squamous tumours Nature Cell Biology · 2013 · 66 citations
    15. Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity Nature Reviews Molecular Cell Biology · 2023 · 200 citations
    16. Foxc1 reinforces quiescence in self-renewing hair follicle stem cells Science · 2016 · 142 citations
    17. Signalling couples hair follicle stem cell quiescence with reduced histone H3 K4/K9/K27me3 for proper tissue homeostasis Nature communications · 2016 · 31 citations
    18. H2AK119ub dynamics control hair follicle stem cell quiescence Nature Communications · 2025 · 2 citations
    19. Dissecting the boundary of quiescence and activation of murine melanocyte stem cells in the hair follicle niche npj Regenerative Medicine · 2026
    20. A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling iScience · 2023 · 1 citations
    21. Understanding The Molecular Mechanisms Of Hair Follicle Stem Cell Quiescence And Genome Plasticity eCommons (Cornell University) · 2013
    22. Transcriptional Governance of Hair Follicle Stem Cell Quiescence and Niche Maintenance in Long-Term Tissue Regeneration Digital Commons - RU (Rockefeller University) · 2025
    23. 320 Desmoglein 3-mediated mechanical transadhesion controls epithelial stem cell quiescence 2021
    24. Quiescent and aging hair follicle stem cells Science · 2016
    25. A New Role for an Old Friend: NFAT and Stem Cell Quiescence Cell stem cell · 2008 · 4 citations
    26. Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence Yearbook of pediatric endocrinology · 2021
    27. NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008 · 415 citations
    28. Epidermal stem cell diversity and quiescence EMBO molecular medicine · 2009 · 168 citations
    29. Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence Cell reports · 2015 · 36 citations
    30. A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth Cell Stem Cell · 2019 · 101 citations