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GlossaryStem Cell Quiescence

state where stem cells remain inactive to preserve function

Stem cell quiescence, also known as stem cell dormancy, refers to a state in which stem cells remain inactive or non-dividing. This state helps protect the stem cells from exhaustion and damage, ensuring they can be activated when needed for tissue repair or regeneration. Quiescent stem cells are crucial for maintaining long-term tissue health and preventing premature aging or diseases like cancer.

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research Quiescent Tissue Stem Cells Evade Immune Surveillance

169 citations, February 2018 in “Immunity”

Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.

The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells

research The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells

35 citations, July 2018 in “Cell Reports”

The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.

research Factors Regulating Quiescent Stem Cells: Insights from the Intestine and Other Self-Renewing Tissues

8 citations, December 2015 in “The Journal of Physiology”

The document concludes that stem cell inactivity is actively controlled and important for tissue repair and balance.

research Molecular Heterogeneity of Quiescent Melanocyte Stem Cells Revealed by Single-Cell RNA-Sequencing

April 2024 in “Pigment cell & melanoma research”

Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.

research Molecular Heterogeneity of Quiescent Melanocyte Stem Cells Revealed by Single-Cell RNA-Sequencing

December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.