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Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

Male hair loss is caused by inactive hair follicle stem cells.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.

The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Different types of stem cells and their environments are key to skin repair and maintenance.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

The HR protein's role as a repressor is essential for controlling hair growth.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Stem cell niches are adaptable and key for tissue maintenance and repair.

Aging in hair follicle stem cells leads to hair graying, thinning, and loss.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

Meis1 is crucial for skin health and tumor development.