Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This article explores the potential mechanisms by which polydeoxyribonucleotide (PDRN) could improve skin quality, slow aging, and enhance skin regeneration, but reports no new clinical findings.

This study found that Hydroxypinacolone Retinoate (HPR) may alleviate UV-induced skin photoaging by enhancing collagen synthesis, reducing degradation, and modulating inflammatory and oxidative responses in a dose-dependent manner.

This study suggests that hydroxypinacolone retinoate (HPR) may be an effective alternative to tretinoin for anti-aging skin treatments, offering similar collagen production benefits without increased skin irritation.

This article reviews the possible therapeutic activities of Angelica gigas Nakai root extracts and their components, noting their potential effects on neuro-cognitive, metabolic, and other health conditions, and reports no new clinical results.

This study found that applying a formulation derived from Bacopa procumbens significantly promoted hair growth, pigmentation, and follicular cycle acceleration in mice compared to minoxidil, potentially offering a new therapeutic approach for hair health.

This study suggests that the herbal formulation Phyllotex™ may promote hair growth in androgenetic alopecia by enhancing cell proliferation and reducing oxidative stress and TGF-β1 expression in vitro.

This study reported that peanut callus extract, rich in resveratrol, significantly stimulated hair growth and reduced hair loss in an in vitro model and a clinical trial, showing promise as a cosmetic bioactive ingredient.

This study found that compounds from *Tectona grandis* leaves showed moderate inhibition of steroid 5α-reductase, a factor in androgenetic alopecia, and exhibited anti-inflammatory properties by inhibiting nitric oxide and pro-inflammatory cytokines IL-1β and IL-6 in vitro, suggesting potential dual-action benefits for AGA management.

In this study, computational analysis identified six molecules, including Jamogenin, as effective in binding to the enzyme 5-alpha reductase (5-AR) from herbal extracts like nettle, saw palmetto, and fenugreek, suggesting potential for hair loss treatments.

This study found that the topical application of a mixture of Platycladus orientalis leaf extract and α-terpineol promoted hair growth in mice by inducing early anagen transition and increasing growth factor expressions.

In this study, the novel topical agent PP405 showed favorable tolerability and increased hair density by over 20% in men with advanced androgenetic alopecia after eight weeks, suggesting a promising potential treatment pending further trials.

In this experimental study, the researchers observed that Platycladus orientalis leaf extract promoted hair growth by enhancing dermal papilla cell proliferation and increasing growth factor expression, particularly through ACK1 activation and modulation of Wnt/β-catenin signaling pathways in cultured human cells and a 12-week topical application.

In this study, human cell models of hair follicles showed that araliadiol, a plant-derived polyacetylene compound, promotes hair growth through the p38/PPAR-γ signaling pathway, suggesting its potential as a new drug candidate for alopecia treatment.

This review summarizes the bioactive compounds and pharmacological functions of Cynomorium songaricum Rupr., emphasizing its potential in developing health-related products, and notes that further research is needed.

This study found that pectin lyase-modified red ginseng extract (GS-E3D) may promote hair growth by enhancing antioxidant and anti-inflammatory effects, proliferating hair dermal papilla cells, and inhibiting 5α-reductase activity.

This study found that palmitoylethanolamide may stimulate allopregnanolone synthesis and reduce oxidative stress in astrocytes through PPAR-α activation, suggesting a neuroprotective role.

Cedrol promotes hair growth better than baricitinib by regulating immune cells.

This study found that procyanidin oligomers bind to keratin and inhibit oxidative hair damage, suggesting their potential use in protective hair care products.

This study suggests that finasteride may inhibit the enzyme phenylethanolamine N-methyltransferase, which could contribute to its sexual and psychological side effects.

This study found that naringin, a natural flavonoid, significantly improved hair growth in mice by activating the Wnt/β-catenin pathway, with the 4% concentration showing comparable efficacy to 5% minoxidil, suggesting naringin as a promising alternative for alopecia treatment.

This issue contains notes by Dr. Bradley Wolf and mentions comments by Dr. Jerry Cooley, but it presents no new research findings.

This study found that PX-12 inhibited the NLRP3 inflammasome and reduced psoriasis-like symptoms in a mouse model, suggesting its potential as a treatment for psoriasis.

Gynostemma pentaphyllum extract may help grow hair and prevent graying.

Platycodon grandiflorum extracts may help prevent hair loss and fight dandruff.

In this study, the researchers reported that a newly developed PYGL inhibitor, HTPI, enhanced hair growth in an ex-vivo culture by reducing oxidative damage in hDPCs and inhibiting glycogen degradation in hORSCs, showing potential as a treatment for hair loss comparable to minoxidil.

This study identifies various phytochemicals in Thuja orientalis bark, potentially aiding its botanical identification and quality standardization.

This laboratory study found that PI extract, along with its metabolites Ang and Mac, inhibited cell proliferation and protein expression linked to pathways involved in BPH, suggesting potential for therapeutic use, although the Ang-Mac combination showed no significant effect on apoptosis through the p53 pathway.