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Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Macroalgae compounds offer sustainable, effective benefits for cosmetics.

Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.

Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.

The project created a standardized system for classifying skin lesions in lab rats and mice.

Mouse genital development depends on male or female hormones for specific features.

A form of vitamin E promotes hair growth by activating a specific skin pathway.

RANKL causes lymph nodes to grow by making certain cells multiply.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

Non-coding RNAs could help detect and treat radiation damage.

Neuregulin3 affects cell development in the skin and mammary glands.

Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

Mast cells likely promote skin scarring and fibrosis, but their exact role is still unclear.

Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Notch signaling disruptions can cause various skin diseases.

Thallium, mercury, selenium, and colchicine strongly cause hair loss.

The document concludes that more multidisciplinary research is needed to understand and treat PCOS, a condition that significantly affects women's health and quality of life.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

VDR regulation varies by tissue and is crucial for its biological functions.

Vitamin D is crucial for bone health and preventing serious diseases.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.