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This study found that COL17 deficiency in neonatal mice causes abnormal skin cell proliferation due to disrupted Wnt signaling, while replenishing or overexpressing COL17 can reverse this effect in both neonatal and aged skin.

This study suggests that vitamin A influences the immune response and hair cycle, affecting the progression of alopecia areata in mouse models.

This study identified a target relationship between miR-148a, miR-10a, and BMP7, suggesting these microRNAs influence dermal papilla cell proliferation and may regulate hair follicle growth.

This review discusses the role of hair follicle stem cells as active signaling centers in skin homeostasis, highlighting recent advancements and reporting no new clinical results.

In this study, the researchers identified a variant in the CCHCR1 gene associated with an alopecia areata subtype characterized by impaired keratinization and autoimmune events.

This study found that keratin 17 expression is initially down-regulated and later strongly up-regulated by ionizing radiation in a rat model, with p53 repressing early transcription.

A new genetic mutation in mice causes permanent hair loss and skin wrinkling.

This study found that the cytokine-mediated signaling pathway is the primary pathway disrupted in skin after CO2 laser surgery.

This study found that hexane extracts of Nostoc verrucosum significantly inhibited melanin synthesis in melanoma cells and demonstrated antioxidant activity, suggesting potential use in developing cosmetic and functional food products.

This study identified a novel SCF mRNA splice variant in white merino sheep skin, which may play a role in hair follicle melanogenesis.

Runx1 helps control the KAP5 gene in human hair follicles.

This review highlights that gut dysbiosis and bacterial extracellular vesicles are key factors in PCOS pathophysiology, and suggests AI-driven analysis of these profiles could enhance diagnostic accuracy and treatment personalization, though ethical concerns like data privacy and bias must be considered.

This study reports that patients with specific MFN2 mutations, including p.Arg707Trp, exhibit significant upper body fat overgrowth with suppressed leptin production, suggesting tissue-selective mitochondrial dysfunction and potential therapeutic targets.

RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.

Targeting S100 proteins may help treat hair loss.

This study suggests that specific mutations in the MFN2 gene, including the p.Arg707Trp allele, can result in tissue-selective mitochondrial dysfunction leading to excessive upper body fat growth and low leptin levels.

This review discusses the complexities of hidradenitis suppurativa pathogenesis, highlighting issues with Notch signaling, immune dysregulation, and the role of keratinocytes and ECM, but reports no new clinical results.

This study found that human hair follicle dermal papilla cells grown in a 3D model influenced hair growth and immune pathways more effectively than those grown in a 2D culture.

This review discusses the complexity of identifying hair follicle antigens involved in alopecia areata and reports no new clinical results, emphasizing the need for further research on autoantigen identity.

This review discusses the development, lineages, functions, and roles of fibroblasts in fibrosis across four organs, highlighting their capabilities in tissue repair and contributions to fibrotic disorders when aberrantly activated, but it reports no new experimental findings.

Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.

This study found that disrupting the Sox21 gene in mice led to progressive hair loss and regrowth, identifying Sox21 as a key regulator of hair shaft cuticle differentiation.

This study suggests that a novel micropatterned dermal–epidermal matrix (μDERM) enhances keratinocyte function and epidermal morphology, offering potential improvements in skin substitute design for wound healing applications.

This study identified numerous genes that change expression across the anagen, catagen, and telogen stages of cashmere goat hair follicle development, highlighting key signaling pathways involved.

This study found that 17β-estradiol inhibited RANTES production in human keratinocytes by suppressing nuclear factor κB activity, suggesting a potential mechanism for 17β-estradiol's modulation of psoriasis-related inflammation.

This study reports that the autotaxin–LPA–LPA3 signaling pathway at the embryo-epithelial boundary plays a critical role in decidualization by up-regulating HB-EGF and COX-2 in the uterine epithelium.

This study found that transcription factors HOXC13, LEF1, and FOXN1 repress DSG4 transcription, with the Notch pathway possibly involved in maintaining DSG4 expression in hair follicles.

This study identified significant gene expression differences in human basal cell carcinoma, including up-regulation of zinc finger encoding genes, which are not entirely reflected in current mouse models.

This review evaluates in vitro hair follicle models, techniques, and challenges without reporting new clinical results, emphasizing their future potential in hair transplantation.

This study found that disrupting Sox21 in developing teeth leads to severe enamel hypoplasia, regional osteoporosis, and abnormal hair formation, with impaired dental epithelial differentiation and regulation of hair follicle cell fate.