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Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Acyzol could help treat conditions caused by zinc deficiency.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Some common medications can harm male fertility, but many effects can be reversed.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Finasteride has a higher risk of reproductive side effects than minoxidil.

PGD2 stops hair growth and is higher in bald men with AGA.

Various medicinal plants like Polygonum multiflorum, Red ginseng extract, and Zizyphus jujuba can potentially treat hair loss, offering benefits like low cost and multiple ways of working. Other effective natural substances include Pygeum africanum, Seneroa, Urtica dioica, and more.

Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Finasteride reduces movement issues in Parkinson's disease rats.

Finasteride helps hair growth but may cause sexual side effects and depression.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

The document concludes that hair loss is influenced by genetics and other factors, and while treatments like finasteride can help, they have limitations and side effects.

Plant-based chemicals may help hair growth and prevent hair loss but need more research to compete with current treatments.

Trazodone and chlorpromazine may help treat sexual dysfunction caused by finasteride and SSRIs.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Resistance exercise can reduce muscle protein issues caused by finasteride.

Finasteride doesn't affect omeprazole metabolism in Japanese people.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Finasteride may improve prostate cancer treatment outcomes.