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Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.

5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Dutasteride works better than finasteride for preventing and treating prostate cancer.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Dutasteride does not impair mental function in elderly men with enlarged prostate.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Finasteride has a higher risk of reproductive side effects than minoxidil.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

Rice bran extract might help prevent hair loss.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Hair loss needs more research for better treatments.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Some plants may help with hair growth and have fewer side effects than synthetic drugs, but more research is needed to confirm their effectiveness.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Stem cell technologies and regenerative medicine, including platelet-rich plasma, show promise for hair restoration in treating hair loss, but more research is needed.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Finasteride doesn't affect omeprazole metabolism in Japanese people.