research Benefits of Testosterone Replacement and Methods of Substitution
Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
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research In Silico Screening of DrugBank Compounds as Potential Inhibitors for Human Steroid 5α-Reductase 2 for Androgen-Related Diseases
Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.
research Can We Predict Prostate Size by Scoring Baldness? The Relationship of Androgenic Alopecia and Lower Urinary Tract Symptoms
Baldness score can't be used to predict prostate size.
research Phytochemicals With Anti 5-Alpha-Reductase Activity: A Prospective For Prostate Cancer Treatment
Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.
research Stability-Indicating Micellar Electrokinetic Chromatography Method for Determination of Finasteride in Pharmaceutical Preparations
Method accurately measures finasteride concentration in medicine.
research Encapsulation of Curcumin in Polystyrene-Based Nanoparticles: Drug Loading Capacity and Cytotoxicity
Curcumin can be effectively loaded into polystyrene nanoparticles, which are safe for human cells and more biocompatible with curcumin inside.
research Chronic Exposure With 5-Alpha Reductase Inhibitor Ameliorates Anxiety and Depression-Like Behaviors by Reducing Systemic Oxidative Stress in D-Galactose-Induced Aging Male Rats
Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.
research Finasteride Attenuates Pathological Gambling in Patients With Parkinson's Disease
Finasteride reduces gambling symptoms in Parkinson's patients.
research Synthesis and Biological Evaluation of Novel Unsaturated Carboxysteroids as Human 5α-Reductase Inhibitors: A Legitimate Approach
New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
research Biotransformation of Finasteride by Ocimum Sanctum L., and Tyrosinase Inhibitory Activity of Transformed Metabolites: Experimental and Computational Insights
Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.
research Incomplete Recovery of Erectile Function in Rats After Discontinuation of Dual 5-Alpha Reductase Inhibitor Therapy
Rats had lasting erectile problems after stopping a certain medication.
research Therapeutic Hotline: Finasteride, 1 Mg Daily Administration on Male Androgenetic Alopecia in Different Age Groups: 10-Year Follow-Up
Finasteride is a safe and effective long-term treatment for male hair loss, especially when started early.
research Simultaneous Estimation of Finasteride and Tamsulosin Hydrochloride in Combined Dosage Forms by RP-HPLC-PDA Method
The method accurately measures Tamsulosin and Finasteride in medication and is suitable for regular quality checks.
research A Population-Based Study of the Risk of Osteoporosis and Fracture with Dutasteride and Finasteride
Dutasteride and finasteride have similar risk for osteoporosis and fractures in older men.
research Global Online Interest in Finasteride Sexual Side Effects
Public interest in finasteride's sexual side effects has significantly increased.
research Prospective Randomized Study of Sexual Function in Men Taking Dutasteride for the Treatment of Androgenetic Alopecia
Dutasteride safely treats hair loss without harming sexual function.
research Stability Study of Finasteride: Stability-Indicating LC Method, In Silico and LC-ESI-MS Analysis of Major Degradation Product, and an In Vitro Biological Safety Study
Finasteride's stability and safety confirmed through precise analytical methods.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research In Vitro Performance of Dutasteride-Nanostructured Lipid Carriers Coated with Lauric Acid-Chitosan Oligomer for Dermal Delivery
Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.
research Association Between 5-Alpha Reductase Inhibitor Use and the Risk of Depression: A Meta-Analysis
Using 5-alpha reductase inhibitors may increase the risk of mild depression.
research Serum Triglyceride Concentration and Risk of Prostate Cancer: A Prospective Multicenter Study
Serum triglyceride levels are not linked to prostate cancer risk.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Insulin Resistance, Nitric Oxide, and Fibrinogen Levels in White Hirsute Women: Defining a New Paradigm Based on Translational Research
White hirsute women with PCOS have higher insulin resistance, but similar nitric oxide and fibrinogen levels compared to those with idiopathic hirsutism.
research 5α-Reductase Inhibitory Potential of Hibiscus Rosa Sinensis: Effective for the Management of Alopecia
Hibiscus rosa sinensis may help manage hair loss.
research Crystal Structure of 17-Beta-Benzoyloxy-16-Beta-Methylpregna-4,6-Diene-3,20-Dione
A new antiandrogen compound was made and its detailed three-dimensional shape was described.
research Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo
Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
research Determination of Finasteride and Related Compounds by Reversed-Phase High Performance Liquid Chromatography: Choosing the Mobile Phase Composition
Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.
research Trends in the Pharmacotherapy of Nocturia, 2016-2021: Analysis of a Large Multi-Institutional Research Network
Nocturia cases increased, but medication use declined, suggesting under-treatment.
research Periungual Lesions Secondary to Chemotherapy with Docetaxel
Chemotherapy with docetaxel can cause painful nail and skin side effects that may lead to stopping treatment.
research Altered Methylation Pattern of the SRD5A2 Gene in the Cerebrospinal Fluid of Post-Finasteride Patients: A Pilot Study
Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.