Therapeutic Hotline: Finasteride, 1 Mg Daily Administration on Male Androgenetic Alopecia in Different Age Groups: 10-Year Follow-Up

    January 2011
    A. M. Rossi, Carmen Cantisani, Marco Scarnò, A Trucchia, Maria Caterina Fortuna
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    TLDR Finasteride is a safe and effective long-term treatment for male hair loss, especially when started early.
    The study evaluated the long-term efficacy of finasteride 1 mg daily in 118 men with male androgenetic alopecia (AGA) over a 10-year period. It found that patients over 30 years old and those with higher AGA grades (IV and V) showed more improvement, with 21% of all patients showing better results after continuing treatment beyond 5 years. While 42.8% of patients aged 20-30 years saw no improvement after 10 years, 58.9% of patients with AGA grade IV and 45.4% with AGA grade V improved after 1 year. Overall, 65% of patients initially improved and then showed no further change, 14% worsened, and side effects were reported by 6% of patients, with 5.1% experiencing reduced libido. The study concluded that finasteride's effectiveness can be predicted after the first year, does not diminish over time, and is a safe and effective long-term treatment for AGA, especially when started early.
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      community Why is everyone not directly advised Dutasteride?

      in Finasteride/Dutasteride  167 upvotes 2 months ago
      Dutasteride is less commonly prescribed for hair loss because it is not FDA-approved for this purpose, unlike finasteride, which is more accessible and preferred due to fewer side effects. Dutasteride may be more effective in reducing DHT but has a longer half-life and potentially more significant side effects.

      community Anyone else growing tired of the finasteride wars?

      in Finasteride/Dutasteride  169 upvotes 1 year ago
      The conversation is about differing experiences with finasteride for hair loss, with some users reporting side effects and others not, and the debate over the drug's safety and effectiveness. Specific treatments mentioned include finasteride, dutasteride, and topical finasteride.

      community Hair loss treatment tier list by Dr Oscar Muñoz

      in Treatment  919 upvotes 4 months ago
      Dr. Oscar Muñoz's hair loss treatment tier list suggests oral minoxidil and finasteride are highly effective, while topical treatments like RU58841 and microneedling are less effective. Users discuss the effectiveness of various treatments, with some favoring oral options for their practicality and higher response rates.

      community Massive study on finasteride side effects released

      in Finasteride/Dutasteride  83 upvotes 1 year ago
      The release of a study on 5a-reductase inhibitors (finasteride and dutasteride) which showed an increased risk of depression, dementia, decreased libido, and reduced semen load as potential side effects; discussion around other forms of hair loss treatments such as topical minoxidil, RU58841, or opting to accept baldness; and advice to consider professional help for deeper issues related to hair loss.

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