An Anti-Hair Loss Treatment in the Management of Mild Androgenetic Alopecia: Results from a Large, International Observational Study

September 2021 in “ Dermatologic Therapy ”

Pascal Reygagne, Victor Desmond Mandel, Catherine Delva, Michaela Havlíčková, Kamila Padlewska, Rose Khalil, Veronique Meuleman, Gilberto Adame Miranda, Mariya Nevskaya, Jean-François Michelet, Florence Pouradier, Sergio Vano-Galvan, Delphine Kerob

androgenetic alopecia AC5 hair loss hair quality AGA

TLDR AC5 improves hair loss and hair quality with high satisfaction rates.

The study evaluated the efficacy of AC5, a cosmetic product, in treating mild androgenetic alopecia (AGA) in 357 subjects (214 women and 143 men) across six countries over 3 months. Results showed that 89% of subjects experienced improved hair loss, with slightly better outcomes in women (92.5%) than men (83.8%). Hair quality was rated as satisfactory or highly satisfactory by 92.4% of subjects, and 96.7% of investigators were satisfied with AC5's benefits, with 98.4% recommending its further use. Subject satisfaction was high, with a mean score of 7.9 out of 10, and tolerability was rated good to very good by 98.6% of subjects. Despite limitations such as the observational design and lack of objective clinical assessments, the study confirmed that AC5 improves hair loss and hair quality with high satisfaction rates.

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Research cited in this study

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research An Anti-Hair Loss Treatment in the Management of Mild Androgenetic Alopecia: Results from a Large, International Observational Study

1 citations, September 2021 in “Dermatologic Therapy”

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35 citations, January 2014 in “BioMed Research International”

Female pattern hair loss involves hormonal factors, genetics, and may be linked to low ferritin levels.

research Female Pattern Alopecia: Current Perspectives

42 citations, August 2013 in “International Journal of Women's Health”

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

research Examining the Relationship Between Alopecia Areata, Androgenetic Alopecia, and Emotional Intelligence

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Men with hair loss experience lower quality of life, worsened by factors like age, severity, and treatment history.

research Female Pattern Hair Loss: Current Treatment Concepts

50 citations, January 2007 in “PubMed”

Minoxidil 2% and 5% are common treatments for female pattern hair loss, with other options including anti-androgens, oral contraceptives, and hair transplantation.

Nudging Hair Shedding by Antidandruff Shampoos: A Comparison of 1% Ketoconazole, 1% Piroctone Olamine, and 1% Zinc Pyrithione Formulations

research Nudging Hair Shedding by Antidandruff Shampoos: A Comparison of 1% Ketoconazole, 1% Piroctone Olamine, and 1% Zinc Pyrithione Formulations

43 citations, October 2002 in “International Journal of Cosmetic Science”

All three shampoos reduced dandruff and hair loss, but ketoconazole and piroctone olamine also made hair thicker.

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