Serum Triglyceride Concentration and Risk of Prostate Cancer: A Prospective Multicenter Study

A prospective multicenter study investigated the relationship between serum triglyceride levels and prostate cancer risk. The study included 194 newly diagnosed prostate cancer cases and 317 controls without malignant disease. After adjusting for potential confounders, the mean serum triglyceride levels were found to be 141.24±74.39 mg/dl in cases and 143.38±71.51 mg/dl in controls, with no statistically significant difference (p=0.76). The odds ratio for the highest versus the lowest tertile of serum triglyceride concentration was 1.24 (95% CI: 0.08-3.12; P=0.18), indicating no significant association between serum triglyceride levels and prostate cancer risk. The findings did not support the hypothesis that serum triglyceride levels are involved in the pathogenesis of prostate cancer.