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This study found that four new progesterone derivatives reduced prostate weight in gonadectomized hamsters, suggesting potent in vivo antiandrogenic effects similar to finasteride.

This study found a negative correlation between dietary monoene levels, particularly oleic acid, and the capacity for PGE₂ synthesis in rat skin, with the most severe skin issues noted in those fed Zephyr rapeseed oil.

This study found that a cosmetic formula containing 2% Orthosiphon stamineus leaf extract significantly reduced skin oiliness and pore size, showing better results than a formula with 1% zinc gluconate.

This study found that the phytosterols β-sitosterol, stigmasterol, and campesterol have low-to-negligible inhibitory activity against steroidal 5α-reductase type 2 compared to the synthetic inhibitor dutasteride, with β-sitosterol showing the highest activity among the tested phytosterols.

This review discusses the potential of phytochemicals from plants as alternative treatments for prostate cancer, highlighting their possible benefits over current 5-alpha-Reductase inhibitors, but reports no new findings.

This study suggests that the dipeptide Pro-Ile has FGF18-like activity, can penetrate model human epidermis, and may have potential as a cosmetic ingredient for skin and hair regulation.

This study demonstrates that pea sprout extract promotes hair growth by activating specific signaling pathways and providing antioxidant and anti-inflammatory effects, suggesting its potential as a natural alopecia treatment.

This review by St. Denis et al. highlights that prostaglandin E2 is overexpressed in several skin cancers and suggests targeting its pathway could offer potential treatments for these malignancies.

This review examines how different prostanoids and their receptors affect hair growth but provides no new clinical results; it highlights potential implications for treating hair disorders.

This review explores plant-derived phytochemicals, such as phytosterols, polyphenols, and fatty acids, for their potential use as alternative treatments for prostate cancer, emphasizing their effects on 5-alpha-Reductase enzyme isozymes. It reports no new clinical results.

This study found that several new pregnane derivatives, especially steroids 16 and 19, demonstrated higher antiandrogenic activity on male hamster models than the commonly used finasteride.

This review explores the therapeutic applications of bimatoprost, including its role in glaucoma treatment, hair growth stimulation, and potential effects on fat deposition, but reports no new experimental findings.

Prostaglandin helps regenerate hair follicles after radiation damage.

This study identified a thiazolidine dione derivative as a potential inhibitor of 15-PGDH that may enhance prostaglandin activity in hair follicles, suggesting its use to support hair regrowth treatments.

This source highlights that while plant sterols show potential benefits and applications in various industries, significant research gaps, including their complex structures and mechanisms, hinder their broader use, emphasizing the need for innovative sources and sustainable methods for their study.

This review discusses plant-derived phytochemicals, such as phytosterols, polyphenols, and fatty acids, as potential alternatives to 5-alpha-reductase inhibitors for prostate cancer treatment, highlighting their promising anti-cancer properties and potentially fewer side effects compared to conventional drugs.

This study demonstrated that α-phellandrene promotes dermal papilla cell proliferation through a cAMP-mediated pathway and upregulates VEGF expression, suggesting its potential use in hair loss prevention.

This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.

This study found that prostasin's proteolytic activity is necessary for normal hair follicle development in mice, but not for interfollicular epidermal development.

This study found that cortexolone 17α-propionate showed strong topical antiandrogenic activity, outperforming progesterone and several known antiandrogens, but lacked systemic antiandrogenic effects in animal models.

This study found that para rubber seed oil, rich in specific fatty acids, effectively protected human epidermal coculture cells from UV-induced damage by reducing inflammatory markers and enzymes linked to photoaging, indicating its potential as a safe and innovative photoaging treatment.

This study reports that pumpkin seed oil-loaded niosomes significantly decreased hair loss and increased hair growth indicators in vivo, suggesting potential as a natural anti-hair loss therapy.

This study found that sulforaphane may help alleviate hair loss by increasing hair count after 18 weeks of use and enhancing the expression of a DHT-degrading enzyme in cellular models.

This study identified optimal parameters for extracting oil from Urtica dioica roots to maximize phytosterol content, using corn oil and a 1:5 raw material-extract ratio over a 6-hour maceration period.

This review discusses the potential of prostaglandin analogs for hair growth and forms of alopecia, and reports no new clinical results.

This study observed that new trienone compounds consistently showed higher 5alpha-reductase inhibitory activity compared to corresponding dienones across various biological models.

This review discusses the benefits of β-sitosterol, a plant compound found in nuts and seeds, which may lower "bad" cholesterol and help prevent heart disease, cancer, and diabetes, but notes the lack of clinical studies on its safety and effectiveness in humans.

This study found that sulforaphane and its related compounds may promote hair follicle growth in mice, suggesting their potential as treatment agents for androgenic alopecia.

This study found that treprostinil, a prostacyclin analog, significantly delayed fibroblast migration from healthy donors but did not affect fibroblast migration derived from diabetic foot ulcers.