Pea Sprout Extract Promotes Hair Follicle Regeneration Via Anagen Phase Prolongation And Dual Modulation Of Oxidative And Inflammatory Signaling

    November 2025 in “ Journal of Microbiology and Biotechnology ”
    Yujin Kim, So Hyeon You, Dae-Won Yoon, Jung Min Lee, Mi‐Seon Woo, Yea Ji Park, Jun-Pyo Hong, Joon Seok, Beom Joon Kim
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    TLDR Pea sprout extract may help hair regrow by reducing stress and inflammation.
    The study demonstrates that pea sprout extract (PSE) promotes hair follicle regeneration by prolonging the anagen phase and modulating oxidative and inflammatory signaling. In vitro and in vivo experiments showed that PSE activates the Wnt/β-catenin signaling pathway, increases hair growth-promoting factors like IGF-1 and FGF7, and decreases inhibitory factors such as IL-1β and BMP4. PSE's antioxidant and anti-inflammatory properties protect hair follicles from oxidative stress and inflammation, suggesting its potential as a natural treatment for alopecia, though further research is needed.
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