93 citations,
January 1996 in “Clinical Pharmacokinectics” Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
55 citations,
March 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
52 citations,
February 2006 in “Current pharmaceutical design” 5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
20 citations,
November 2019 in “Biomolecules” Finasteride reduces response to stress and rewards, affecting behavior and mental health.
14 citations,
November 2008 in “Expert opinion on drug metabolism & toxicology” Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
4 citations,
December 2011 in “Drug Research” Two finasteride tablet types are equally effective and can be swapped.
3 citations,
October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
December 2011 in “Drug Research” The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.
125 citations,
January 1999 in “Drugs” Finasteride effectively treats baldness but may cause sexual side effects.
86 citations,
July 1993 in “Drugs” Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
56 citations,
April 1998 in “Steroids” Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.
50 citations,
October 2014 in “International Journal of Clinical Pharmacology and Therapeutics” New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
33 citations,
November 2008 in “European Journal of Pharmaceutical Sciences” St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
32 citations,
March 2020 in “Drug Design Development and Therapy” Finasteride shows promise for female hair loss, but more research needed.
21 citations,
October 2014 in “Antimicrobial Agents and Chemotherapy” Finasteride effectively prevents biofilm formation and treats preformed biofilms, but requires high doses.
16 citations,
January 2010 in “Drug Metabolism and Pharmacokinetics” Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.
14 citations,
May 2011 in “Drug Metabolism and Disposition” Ketoconazole increases finasteride's effectiveness and lifespan in the body.
8 citations,
January 1991 in “European Urology” Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.
3 citations,
January 2011 The method measures finasteride accurately and cheaply using UV light.
1 citations,
April 2015 in “Drug research” New method measures finasteride in plasma, finds two formulations bioequivalent.
143 citations,
August 1991 in “Endocrinology” Androgens, like testosterone, are crucial for early testicular descent in rats.
19 citations,
March 2019 in “Behavioural Brain Research” Finasteride use can cause depression-like behavior in male rats.
19 citations,
December 2002 in “Journal of Liquid Chromatography & Related Technologies” New method quickly and accurately measures finasteride in tablets.
8 citations,
August 2011 in “Journal of Pharmacology and Experimental Therapeutics” Dosing time affects finasteride's effectiveness and safety in rats.
5 citations,
June 2008 in “Acta Cirurgica Brasileira” Finasteride causes sperm production decrease in Mesocricetus auratus.
June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” Finasteride improves hair growth in men with androgenetic alopecia.
1 citations,
February 2022 in “Brain Research Bulletin” Finasteride may help reduce impulsivity caused by pramipexole.
October 2023 in “Journal of pharmaceutical investigation” Finasteride dosages should be adjusted based on CYP3A5 genotype and liver function to avoid side effects.
June 2024 in “Advances in therapy” IVL3001 is safe, effective, and better than oral finasteride for treating hair loss.
11 citations,
March 2009 in “Bioorganic & Medicinal Chemistry Letters” Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.