UV Spectrophotometric Method for Determination of Finasteride in Bulk and Pharmaceutical Dosage Form

January 2011

Manish Kumar Thimmaraju, Venkat K. Rao, Srikanth Gurrala, G Jayapal Reddy

finasteride UV spectrophotometric method chloroform absorbance pharmaceutical dosage form Propecia

TLDR The method measures finasteride accurately and cheaply using UV light.

The document from 2011 detailed a UV spectrophotometric method for measuring finasteride in both bulk and tablet forms, which was found to be simple, quick, accurate, and cost-effective. Finasteride was dissolved in chloroform and its absorbance was measured at 245 nm, with a demonstrated linearity in the 10 – 120 μg/ml concentration range and a high correlation coefficient of 0.9993. The method's precision and accuracy were confirmed by a relative standard deviation of 0.2319 and recovery studies, which showed percentage recoveries ranging from 99.09% to 99.92%. This method was validated for routine use and was not affected by the presence of excipients and additives in pharmaceutical formulations.

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Research cited in this study

1 / 1 results

research Polarographic Behavior and Determination of Finasteride

21 citations, February 2003 in “Farmaco”

Method quickly measures finasteride concentration in capsules.

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research Development and Validation of UV Spectrophotometric Method for the Estimation of Finasteride Drug

December 2019 in “International journal of pharmaceutical quality assurance”

A reliable UV method was created to measure finasteride accurately.

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