9 citations,
July 2022 in “Cell reports” Sox2 controls hair color by affecting pigment production in hair follicles.
173 citations,
January 2014 in “Nature Cell Biology” Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.
86 citations,
June 2017 in “Stem cell investigation” Stem cells from hair follicles can safely treat hair loss.
30 citations,
April 2010 in “Cell Cycle” The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.
28 citations,
October 2019 in “Seminars in Cell & Developmental Biology” Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.
68 citations,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
17 citations,
September 2019 in “Journal of Cell Biology” Hair follicle regeneration may slow tumor growth.
1 citations,
January 2022 in “Cell Biology International” Changing CDK4 levels affects the number of stem cells in mouse hair follicles.
20 citations,
November 2021 in “Frontiers in cell and developmental biology” Skin organoids from stem cells could better mimic real skin but face challenges.
5 citations,
January 2021 in “Frontiers in Cell and Developmental Biology” Inhibiting Zyxin may help treat androgenetic alopecia by promoting hair growth.
24 citations,
September 2019 in “Experimental cell research” BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.
2 citations,
July 2022 in “Stem cell research & therapy” A new method quickly and efficiently isolates hair follicle stem cells from adult mice, promoting hair growth.
20 citations,
July 2019 in “Stem cell investigation” Combining SVF and PRP speeds up wound healing.
1 citations,
January 2022 in “Stem cell biology and regenerative medicine” New methods to test hair growth treatments have been developed.
17 citations,
June 2019 in “The journal of immunology/The Journal of immunology” A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
5 citations,
October 2021 in “Frontiers in Cell and Developmental Biology” Fat tissue under the skin affects hair growth and aging; reducing its inflammation may help treat hair loss.
1 citations,
April 2017 in “Journal of Investigative Dermatology” Higher minoxidil dose helps hair growth in non-responders without side effects.
April 2017 in “Journal of Investigative Dermatology” Sweat glands and hair follicles are determined by opposing signals, with BMPs promoting sweat glands and blocking BMPs leading to hair follicles.
April 2017 in “Journal of Investigative Dermatology” The study found a link between the severity of Lichen Planopilaris seen by doctors and the details seen under a microscope, and created a new way to measure this severity.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A new staining method shows a special area in the hair's skin layer with lots of proteoglycans.
April 2016 in “Journal of Investigative Dermatology” Gypenosides from Gynostemma pentaphyllum were found to have anti-aging effects, increasing skin collagen and reducing wrinkles.
April 2016 in “Journal of Investigative Dermatology” Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.
11 citations,
January 2018 in “Acta dermato-venereologica” Researchers found specific genes in the part of hair follicles that could help treat hair disorders.
2 citations,
April 2019 in “Experimental Dermatology” The article concludes that studying how skin forms is key to understanding skin diseases and improving regenerative medicine.
September 2023 in “Nature communications” Alk1 in specific cells is crucial for proper nerve branching and hair function.
159 citations,
October 2015 in “Science Advances” Blocking JAK-STAT signaling can lead to hair growth.
60 citations,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
40 citations,
January 2016 in “Elsevier eBooks” The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.
6 citations,
January 2018 in “Journal of Cellular Physiology” Human scalp fat stem cells showed improved cartilage-like development on a special scaffold with freeze-thaw treatment.
6 citations,
February 2013 in “Journal of Visualized Experiments” The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.