Cyclin-Dependent Kinase 4 Expression Alters the Number of Keratinocyte Stem Cells in the Mouse Hair Follicle

    January 2022 in “ Cell Biology International ”
    Sun Hye Kim, Liliana R.l. Rodriguez, Everardo Macías, Marcelo L. Rodriguez‐Puebla
    Studysummary This study found that altering cyclin-dependent kinase 4 (CDK4) levels in the bulge region of hair follicles affects the balance of stem cell numbers, potentially influencing hair follicle self-renewal and proliferation.
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    Research cited in this study 12

    1. Cyclin-Dependent Kinase 4 Expression Alters the Number of Keratinocyte Stem Cells in the Mouse Hair Follicle Cell Biology International · 2022
    2. Cyclin D3 Deficiency Inhibits Skin Tumor Development But Does Not Affect Normal Keratinocyte Proliferation Oncology Letters · 2017
    3. A Keratin 15 Containing Stem Cell Population From the Hair Follicle Contributes to Squamous Papilloma Development in the Mouse Molecular Carcinogenesis · 2012
    4. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    5. Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008
    6. CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice Cancer Research · 2007
    7. Stem Cells in the Hair Follicle Bulge Contribute to Wound Repair but Not to Homeostasis of the Epidermis Nature Medicine · 2005
    8. Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells Genes & development · 2005
    9. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
    10. Enrichment for Living Murine Keratinocytes from the Hair Follicle Bulge with the Cell Surface Marker CD34 Journal of Investigative Dermatology · 2003
    11. Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells Cell · 2001
    12. The Biology of Hair Follicles The New England Journal of Medicine · 1999

    Related research 2

    1. Keratinocyte Stem Cells: Role in Aging IntechOpen eBooks · 2022
    2. Cyclin-Dependent Kinase 4 Expression Alters the Number of Keratinocyte Stem Cells in the Mouse Hair Follicle Cell Biology International · 2022