Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

Hair follicle stem cells help maintain skin health after injury.

This review discusses the potential of the hair follicle dermis to direct hair development and explores concepts related to hair growth and androgenetic alopecia, without reporting new clinical results.

This study explored the regenerative abilities of the African spiny mouse's skin, revealing more robust wound-induced hair follicle neogenesis compared to laboratory mice and highlighting unique features of its hair and wound response.

This study found that full thickness wounds in Lanyu pigs led to altered molecular expression and abnormal skin structure, without regenerating key epithelial cells thought to aid in skin regeneration.

This review discusses mechanisms of wound healing impairment in leptin-deficient murine models used for diabetic research, and reports no new clinical results; the authors emphasize the need for further study.

FGF9 from certain T cells helps create new hair follicles during wound healing, which could potentially be used for hair loss treatments.

A substance called FGF9 from certain immune cells can trigger new hair growth during wound healing in mice, but humans may not have the same response due to fewer of these cells.

FGF9 from certain cells can trigger new hair growth during wound healing, but humans have fewer of these cells, which may limit hair regrowth.

Hair can regrow in adult mice's skin after injury, and this process can be boosted by increasing Wnt7a, a protein. This could potentially help treat baldness and change our understanding of hair growth.

Hair can regrow in adult mice's skin after injury, and this regrowth doesn't come from existing hair cells but from skin cells in the wound, with Wnt7a protein helping this process. This could help treat baldness and scarring.

This study found that fibroblast growth factor 9, initially secreted by γδ T cells, plays a key role in modulating hair follicle regeneration in mice after skin wounds.

This study presented a case series of erosive pustular dermatosis on the scalps of elderly patients, noting unusual presentation with hypergranulation tissue and unique dermoscopic vascular patterns, diverging from typical manifestations.

This study found that hair follicle stem cells initially contribute to wound re-epithelialization, but long-lasting epidermal cells are primarily derived from a stem cell population in the isthmus portion of hair follicles.

This study found that the microRNA miR-22 is a key regulator of the hair cycle, influencing hair loss by promoting the transition from growth to rest phases and repressing keratinocyte differentiation.

This study found that the GPR39 receptor plays a novel role in accelerating wound healing in mouse skin, although it is not essential for skin development or homeostasis.

This study suggests that the InlB321/15 protein may accelerate wound healing by increasing cell proliferation and reducing wound closure time in both cell culture and mouse models.

This study identified a set of wound-induced genes in planarians that play a role in regeneration initiation, with some genes specifically activating within regenerative cells called neoblasts.

In this study, researchers found that electrospun membranes with aligned surface topography advanced the immune response towards an adaptive stage and highlighted the role of T cells in hair follicle regeneration in mice, showcasing the intricate interactions between immune and skin cells.

This study found that adipose-derived mesenchymal stem cells from type 2 diabetes mice were slightly less effective, yet had comparable therapeutic effects on wound healing compared to non-diabetic controls.

This study found that reduced cell cohesiveness in eccrine sweat gland outgrowths contributed to delayed wound healing in elderly skin compared to younger skin.

This study found that using cultured mesenchymal stem cells from mouse whisker hair follicle outer root sheath in wound healing reduced inflammation, accelerated closure, and resulted in less hypertrophic scarring in mice.

This article reviews skin regeneration and fibrosis, identifying key cellular and molecular players, and emphasizing the potential to manipulate the postwound environment to promote regeneration over fibrosis.

This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.

This review covers recent findings on stem cell plasticity under normal and cancerous conditions but presents no new experimental results, highlighting implications for regenerative medicine and cancer treatments.

This study reported that administering salicylates to wounds in adult mice promoted wound healing patterns similar to embryonic wounds, enabling complete wound regeneration and reduced scarring by activating AMPK and subsequent signaling pathways.

This study found that hair follicles in mice and humans can convert wound-related myofibroblasts into adipocytes, suggesting a potential pathway to reduce scar formation by activating BMP signaling.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

This study found that β-catenin signaling increases in newly born glial cells in the cortex after traumatic brain injury in mice, suggesting potential targets for enhancing recovery through the Wnt/β-catenin pathway.

This review highlights that the RNA modification N⁶-methyladenosine (m⁶A) plays a crucial role in regulating wound healing and tissue remodeling, with dysregulation contributing to complications in chronic wounds, such as diabetic ulcers and burn injuries, through mechanisms like impaired angiogenesis and increased oxidative stress.

This article discusses the advances in understanding wound-induced hair follicle neogenesis (WIHN) and highlights the roles of specific signaling pathways and cellular plasticity, noting no clinical results but suggesting potential areas for further research.