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This review explores the potential benefits of using medicinal plants as an alternative or supplementary therapy for improving reproductive and metabolic health in women with polycystic ovary syndrome, but reports no new results.

This review article highlights recent advancements in smart hydrogels as promising solutions for diabetic wound management, emphasizing their ability to respond to wound environments and deliver targeted therapies, while addressing limitations of traditional dressings.

This study found that insulin resistance varies across different PCOS phenotypes, with the PCOM+MI+HA phenotype showing higher resistance than others.

This study found that procyanidin B-3, a compound isolated from barley extract, may promote hair growth by enhancing hair epithelial cell growth and counteracting TGF-β1's growth-inhibiting effects in vitro and in vivo.

This study found that indole glycosides from Calanthe discolor Lindl. can significantly promote the proliferation of human hair follicle dermal papilla cells, potentially through upregulating specific growth factors.

This study found that among women with polycystic ovary syndrome, insulin resistance was more strongly associated with cardio-metabolic abnormalities than β-cell dysfunction, and they showed different correlations with obesity.

This study found that Greek women with classic PCOS phenotypes have a higher risk of metabolic syndrome and impaired glucose homeostasis compared to those with newer PCOS phenotypes.

The researchers reported that a newly developed photo-cross-linked hydrogel with multifunctional properties, including antimicrobial and antioxidant effects, significantly improved diabetic wound healing, achieving over 90% wound closure in seven days in vivo.

This study reported that women with polycystic ovary syndrome had higher glypican-4 levels compared to controls, indicating its significant role in hormonal regulation associated with the condition.

This review reported that various herbs including cinnamon, fenugreek, and turmeric may effectively treat polycystic ovarian disorder with minimal side effects, suggesting potential for herbal therapies to target the disorder's root causes and improve overall health.

This review indicates promising potential for cinnamon supplementation to improve metabolic outcomes in PCOS, but more clinical trials with higher doses and longer durations are needed to confirm these effects.

This review discusses the therapeutic use of insulin-sensitizing agents in polycystic ovary syndrome, reporting improved ovulation, insulin sensitivity, and reduction of hyperandrogenism, but calls for larger studies to confirm these effects.

This study explores the role of antidiabetic medications, particularly metformin, GLP-1 receptor agonists, and DPP-4 inhibitors, in managing PCOS, highlighting their combination with hormonal therapies and lifestyle interventions for a comprehensive treatment approach.

In this study, the administration of indole-based compounds, particularly L-Tryptophan and Tryptophol, to a PCOS-induced rat model resulted in an increased number of healthy ovarian follicles and a reduction in ovarian cysts compared to untreated rats, suggesting potential therapeutic efficacy.

Polisorbate 20 is not suitable for curl creams due to instability.

This study suggests that glycation of hair proteins in diabetic patients may serve as a useful indicator of long-term blood glucose trends and associations with diabetic complications.

This study identified orally available itaconate derivatives that improve cellular permeability and bioavailability, with specific POC-based prodrugs showing significant inhibition of inflammatory cytokines in human epidermal keratinocytes and favorable oral pharmacokinetics, highlighting their potential for treating systemic and skin disorders.

Some natural compounds might help hair grow.

This study evaluated Tridax procumbens extracts for their in-vitro alpha amylase inhibitory activity compared to standard antidiabetic agents, suggesting potential benefits for diabetes management.

In this study, pioglitazone treatment in insulin-resistant PCOS patients decreased relative 5alpha-reductase activity without significantly affecting cortisol levels or urinary cortisol excretion.

This study found that increasing the proportion of ethanol in minoxidil formulations improved skin penetration in both in vitro and in vivo tests on mice.

In this study, adding TPGS to a minoxidil formulation improved local retention and reduced systemic absorption in certain solvent mixes, particularly with a balance of alcohol and PEG 400.

In this study, treating diabetic rats with mulberry leaf decoction for 14 days lowered blood glucose levels and influenced metabolic and tissue changes related to diabetes.

This study found that, among women with type 1 diabetes, those with polycystic ovary syndrome did not show worse lipoprotein and inflammatory glycoprotein profiles compared to those without the syndrome, although they had more harmful HDL particle subclasses than women with typical PCOS.

This study describes a method to create keratin hydrogels with adjustable erosion rates by mixing different ratios of keratose and kerateine, enabling controlled release of therapeutic agents like insulin-like growth factor 1.

In this study, the researchers reported that a newly developed PYGL inhibitor, HTPI, enhanced hair growth in an ex-vivo culture by reducing oxidative damage in hDPCs and inhibiting glycogen degradation in hORSCs, showing potential as a treatment for hair loss comparable to minoxidil.

This study provides a narrative review suggesting GLP-1 receptor agonists could optimize metabolic health before conception in women with PCOS, but not necessarily improve fertility outcomes, emphasizing individualized use and the need for further research to confirm their reproductive benefits and safety.

This study found that polysaccharide extracts from ginseng, green tea, shiitake, and aloe vera effectively protected human follicle dermal papilla and keratinocyte cells by promoting cell proliferation or inhibiting apoptosis, suggesting potential for these extracts as ingredients in cosmetics or pharmaceuticals to prevent hair loss.

This study found that ex vivo, the skin permeability of caffeine increased with formulations using natural caffeine from coffee extract, particularly when combined with 2.5% Transcutol P, compared to synthetic caffeine formulations.

This study reviews the potential of antioxidant plant compounds in improving wound healing for diabetic patients by reducing oxidative stress, controlling bacterial infections, and modulating inflammation, thereby promoting tissue regeneration and addressing key challenges in diabetic wound care.