Tunable Keratin Hydrogels for Controlled Erosion and Growth Factor Delivery

    December 2015 in “ Biomacromolecules ”
    Trevor R. Ham, R. T. LEE, Sangheon Han … Justin M. Saul
    Studysummary This study describes a method to create keratin hydrogels with adjustable erosion rates by mixing different ratios of keratose and kerateine, enabling controlled release of therapeutic agents like insulin-like growth factor 1.
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    Research cited in this study 10

    1. Alkylation of Human Hair Keratin for Tunable Hydrogel Erosion and Drug Delivery in Tissue Engineering Applications Acta biomaterialia · 2015
    2. Human Hair Keratin and Its-Based Biomaterials for Biomedical Applications Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine · 2014
    3. A Human Hair Keratin Hydrogel Scaffold Enhances Median Nerve Regeneration in Nonhuman Primates: An Electrophysiological and Histological Study Tissue Engineering Part A · 2013
    4. The Effect of Human Hair Keratin Hydrogel on Early Cellular Response to Sciatic Nerve Injury in a Rat Model Biomaterials · 2013
    5. Structure–Property Relationships of Meta-Kerateine Biomaterials Derived from Human Hair Acta biomaterialia · 2011
    6. Mechanical and Biological Properties of Keratose Biomaterials Biomaterials · 2011
    7. Mechanisms of Hepatocyte Attachment to Keratin Biomaterials Biomaterials · 2011
    8. Keratin Hydrogels Support the Sustained Release of Bioactive Ciprofloxacin Journal of biomedical materials research. Part A · 2011
    9. Effect of Keratin-Gelatin and bFGF-Gelatin Composite Film as a Sandwich Layer for Full-Thickness Skin Mesh Graft in Experimental Dogs Journal of Biomedical Materials Research Part B Applied Biomaterials · 2007
    10. The Use of Keratin Biomaterials Derived from Human Hair for the Promotion of Rapid Regeneration of Peripheral Nerves Biomaterials · 2007

    Related research 1

    1. Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins Advances in experimental medicine and biology · 2018