14 citations
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February 2023 in “Frontiers in Bioengineering and Biotechnology” This review details various components used in hydrogel composites for treating chronic diabetic ulcers and highlights potential future materials but reports no new empirical findings.
14 citations
,
September 2023 in “Frontiers in Nutrition” This source observed that while supplementation with pro-, pre-, and synbiotics showed some beneficial effects for PCOS-related outcomes, the evidence quality was deemed low to very low, highlighting the need for further well-designed randomized controlled trials in women with PCOS.
13 citations
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December 2021 in “Toxics” In this study, PEGDE above 10,000 μg/mouse caused subcutaneous toxicity including ulceration in mice, but did not affect liver, spleen, or kidney tissues.
January 2021 in “Research Square (Research Square)” This study identified distinct metabolic differences between PCOS patients and healthy controls, suggesting potential metabolic markers for PCOS prognosis and diagnosis.
6 citations
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December 2022 in “Frontiers in Pharmacology” This review examines the potential therapeutic effects and mechanisms of quercetin for treating polycystic ovary syndrome, noting improved clinical parameters in some studies but presenting no new results.
July 2023 in “Journal of the Mexican chemical society” This study found that Hibiscus rosa-sinensis dried leaves extract displayed the strongest pancreatic lipase inhibitory activity among 37 tested plant extracts, showing potential as an anti-obesity agent with effects comparable to the pharmaceutical drug orlistat in reducing plasma triacylglycerol levels in rats.
February 2025 in “Iraqi Journal of Science” This study found that women with polycystic ovary syndrome had significantly higher serum lactate dehydrogenase levels and lower levels of cortisol, dopamine, zinc, and vitamin D3 compared to healthy controls.
11 citations
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March 2024 in “Current Issues in Molecular Biology” This review discusses the pharmacological actions and potential therapeutic benefits of ginsenoside compound K for metabolic disorders, reports no new clinical results, and suggests further research on its bioavailability and toxicity.
October 2022 in “International journal of pharmaceutical sciences review and research” This study compared the antioxidant and antidiabetic activities of Hibiscus rosa-sinensis leaf extract and Eclipta alba bark extract, finding that Hibiscus rosa-sinensis exhibited greater antidiabetic activity, whereas Eclipta alba demonstrated stronger antioxidant activity.
February 2022 in “Fibers” This study found that a sucrose-based crosslinker can effectively straighten hair and maintain durability in high humidity and through repeated washings without affecting the hair's tensile properties or causing surface damage.
48 citations
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February 2025 in “Advanced Materials” This study found that a glucose-activated hydrogel significantly improved chronic diabetic wound healing by regulating blood glucose and enhancing the wound microenvironment, achieving a threefold increase in recovery rate compared to commercial dressings.
188 citations
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December 2020 in “Foods” This review explores the potential health benefits of food bioactive compounds, specifically polyphenols, as preventive agents against non-communicable diseases like cancer and cardiovascular disorders, while also addressing challenges like bioavailability and industrial applications.
4 citations
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December 2020 in “Natural Product Sciences” This study identified ten compounds from Eclipta prostrata, with some displaying potent inhibitory effects against α-glucosidase and acetylcholinesterase enzymes.
23 citations
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June 2015 in “Clinica Chimica Acta” In this study, researchers identified two potential urinary biomarkers, testosterone–glucuronide and 11α-hydroxyprogesterone, along with four candidate biomarkers, to help understand and diagnose polycystic ovary syndrome.
69 citations
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December 2015 in “BMC plant biology” This study provides evidence that five Hyp-O-GALT genes are crucial for AGP galactosylation and that AGP glycans are vital for various aspects of plant growth and development.
October 2004 in “Australian Prescriber” This review discusses the lack of long-term clinical studies on metformin's cardiovascular benefits in women with polycystic ovary syndrome, highlighting lifestyle changes as a crucial management strategy for reducing associated risks.
August 2024 in “Repozitorij Farmaceutsko-biokemijskog fakulteta (Sveučilišta u Zagrebu)” This study reports that a carbopol gel formulation with melatonin shows potential for extended drug release and biocompatibility in dermal applications due to its favorable bio-pharmaceutical properties.
3 citations
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December 2019 in “International Journal of Pharmacology” This study found that Poria cocos extract may enhance human follicle dermal papilla cell proliferation through the AKT signaling pathway, indicating its potential for hair growth promotion.
1 citations
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March 2009 in “China Journal of Chinese Matera Medica” This review discusses the pharmacological effects and potential mechanisms of procyanidins, noting its roles in antioxidation, cardiovascular protection, and more, but reports no new clinical results.
August 2023 in “Gadua Journal of Pure and Allied Science” This study on diabetic rats reported that Ziziphus spina-christi ethanol leaf extract significantly reduced blood glucose levels and improved liver and kidney function, suggesting possible benefits in managing diabetes symptoms in this animal model.
5 citations
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September 2015 in “Medical hypotheses” This article suggests that a topical sulfonylurea drug may inhibit excessive hair growth caused by diazoxide without affecting its beneficial effects on beta cells, potentially offering a treatment for various forms of hypertrichosis and hirsutism.
This review investigates the relationship between polycystic ovarian syndrome and the development of type 2 diabetes mellitus but reports no new clinical findings.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers developed a multifunctional hydrogel (FVP@CCN) that demonstrated over 90% wound closure in 7 days in diabetic wound models, thanks to its antibacterial, antioxidant, anti-inflammatory, and angiogenesis-promoting properties.
May 2023 in “Metabolites” In this study, adding α-lactalbumin to myo-inositol treatment improved ovulation rates, menstrual cycle duration, and hyperandrogenism in women with PCOS more effectively than myo-inositol alone, suggesting potential benefits for those resistant to inositol treatment.
June 2024 in “Okayama University Scientific Achievement Repository (Okayama University)” In this study, methanol extracts from Thai-colored rice fermented with Aspergillus molds exhibited an increase in polyphenolic content and antioxidant activity, outperforming Thai white and Japanese white rice, notably transforming key polyphenols like quercetin and ferulic acid.
This study found that glycerol most significantly influenced the spreadability and initial viscosity of a saw palmetto anti-hair loss cream, while PEG 400 predominantly affected viscosity changes over time.
11 citations
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April 2019 in “International Journal of Molecular Sciences” This study found that genetic polymorphisms of OCT1 influence the effectiveness of metformin treatment in improving insulin sensitivity among PCOS patients, suggesting a role for personalized treatment strategies.
7 citations
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March 2011 in “Hormone and Metabolic Research” This study found that in PCOS patients, variations in the lipin 1 gene, particularly the intron 1 SNP, may protect against insulin resistance and glucose intolerance, highlighting a potential genetic factor in the disorder's cardiometabolic complications.
3 citations
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March 2007 in “Canadian Medical Association Journal” This abstract provides background information on polycystic ovary syndrome and reports no new research findings.
10 citations
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November 2014 in “Journal of Dermatological Treatment” This review examines clinical trials on polyphenol-based therapies for dermatological conditions, suggesting potential benefits for anogenital warts, alopecia, and acne, but calls for more rigorous trials.