Effect of Indole-Based Derivatives on Rats with Polycystic Ovary Syndrome

    April 2017 in “ Journal of Pharmaceutical Investigation ”
    Parichehreh Yaghmaei, Babak Dehestani, Samira Ghorbani … Azadeh Ebrahim-Habibi
    Studysummary In this study, the administration of indole-based compounds, particularly L-Tryptophan and Tryptophol, to a PCOS-induced rat model resulted in an increased number of healthy ovarian follicles and a reduction in ovarian cysts compared to untreated rats, suggesting potential therapeutic efficacy.
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    Research cited in this study 2

    1. Protective Effects of Melatonin Against Metabolic and Reproductive Disturbances in Polycystic Ovary Syndrome in Rats Journal of Pharmacy and Pharmacology · 2014
    2. Increased Androgen Bioavailability Is Associated With Non-Alcoholic Fatty Liver Disease In Women With Polycystic Ovary Syndrome Human Reproduction · 2009