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Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Finasteride treatment for three years changes certain polyamine levels in the blood but not in urine.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

OM-X® helped prevent negative effects of Vitamin C deficiency in mice, suggesting it could protect organs and regulate metabolism.

No FDA-approved treatments for chemotherapy-induced hair loss existed in 2006; more research was needed.

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

Hairless protein and putrescine regulate each other, affecting hair growth and skin balance.

Polyamines help fix DNA damage accurately in cells.

Certain amino acid analogues can inhibit wool and hair growth and affect fiber strength.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Nutrients like vitamins, copper, zinc, and amino acids are crucial for healthy hair and wool growth.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

The combination of Arginine Silicate Inositol Complex and a new form of Biotin improved hair and nail growth in rats.

Overexpressing a specific enzyme in mice causes hair loss and female infertility.

Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.

Some minoxidil combinations can help differentiate leukemia cells without harming other cells.

Altering SSAT affects fat metabolism and body fat in mice.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Increasing SSAT makes skin more prone to cancer.

Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.

Overexpression of SSAT in mice causes hair loss, liver damage, and sensitivity to polyamine analogues.

Adjusting polyamine levels could help treat skin disorders like psoriasis and skin cancer.