This research found that nod factor can induce root hair reorientation and gene expression in Medicago truncatula with as little as a single molecule, implicating heterotrimeric G-protein signaling in this process.
Combining microneedling with platelet-rich plasma enhances skin repair and collagen production but may not offer significant extra benefits.
13 citations
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October 2010 in “Pharmacogenomics” This study constructed a panel of pharmacokinetic and pharmacodynamic genes, revealing that current SNP chips insufficiently capture many drug-response gene variants, highlighting the need for complementary genetic approaches.
24 citations
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April 2013 in “PLOS ONE” This study identifies substance P, TNFα, and IFNγ as novel regulators of prolactin and its receptor expression in human skin, suggesting intracutaneous prolactin is not controlled by dopamine.
11 citations
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October 2023 in “mSphere” This study reported that the PrrH sRNA in *Pseudomonas aeruginosa* may directly regulate genes involved in pyochelin siderophore biosynthesis, highlighting its role in adapting to heme availability, with light conditions influencing this gene expression.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that cannabinoid receptor type 1 may influence psoriasis development by modulating laminin-511 expression, suggesting a potential target for treatment.
2 citations
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December 2024 in “Journal of Cosmetic Dermatology” In this study, the integration of AI-driven SNP profiling and epigenetic insights in cosmetic dermatology was highlighted as a key development toward personalized skincare, potentially improving treatment effectiveness and reducing side effects.
12 citations
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November 2003 in “Journal of the American Academy of Dermatology” This study found hair regrowth in the majority of AA-affected mice and rats treated with diphencyprone, suggesting its potential utility for understanding human alopecia areata and the drug's therapeutic action.
3 citations
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April 2024 in “JAAD Case Reports” This article reviews DPCP's use as a topical immunotherapy for alopecia areata and discusses its suggested mechanism, but reports no clinical results.
March 2024 in “Journal of pharmacy & pharmaceutical sciences” This review discusses the design strategies and applications of long-acting polymeric microneedles, noting their potential to improve patient compliance and reduce side effects in chronic disease management, but reports no new experimental results.
This study found that CPA-loaded nanoparticles, particularly SLN formulations, increased CPA epidermal penetration compared to a conventional cream and may reduce side effects in treating androgen-dependent conditions.
60 citations
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January 2023 in “Biomaterials Science” This study reviews recent advancements in microneedles made from PLGA, highlighting their use in delivering vaccines, drugs, and proteins through the skin with minimal invasiveness, and discusses the challenges and future potential of these delivery systems.
5 citations
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January 2018 in “PubMed” In this study, applying a biodegradable microneedle patch after topical steroid application significantly increased steroid penetration and improved treatment outcomes in patients with prurigo nodularis compared to the control.
November 2024 in “Journal of Investigative Dermatology” Polygenic Score can help predict severe psoriasis and psoriatic arthritis.
9 citations
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January 2021 in “RSC Advances” Non-thermal plasma helps hair grow by improving the area around hair follicles.
1 citations
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January 2017 in “ARC journal of dermatology” This study introduced and evaluated Ahmad's NPRT system for documenting hair loss, finding it helpful in assessing the specific state of male pattern baldness in 500 patients.
January 2025 in “RSC Advances” This study reported that a new formulation of finasteride solid lipid nanoparticles, combined with LPC and NTC, enhanced hair growth in mice without visible skin reactions, suggesting it could effectively manage androgenetic alopecia.
June 2025 in “Turkish Journal of Dermatology” This study found that patients with acne vulgaris had significantly lower serum paraoxonase 1 (PON1) activity compared to healthy controls, suggesting that oxidative stress might play a role in the condition's development.
November 2022 in “Pakistan Armed Forces Medical Journal” This study found that topical liquid nitrogen improved pain tolerance during intradermal platelet-rich plasma therapy in androgenic alopecia compared to normal saline, although patient satisfaction did not significantly differ between groups.
12 citations
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April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
3 citations
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April 2021 in “PLoS ONE” The authors concluded that controlling voltage, pulse width, and calcium concentration in pulse electric field-activated platelet-rich plasma enhances the release of growth factors and serotonin without causing clot formation, suggesting potential clinical advantages over bovine thrombin-activated PRP.
8 citations
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July 2018 in “European Journal of Dermatology” A medication may help with hair growth in psoriasis, and a skin condition might be linked to a specific bacteria.
15 citations
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June 2015 in “F1000Research” This study examined immune responses to Diphencyprone and found that its induced skin reactions have higher levels of negative immune regulators compared to psoriasis, suggesting differences in immune regulation may contribute to psoriasis chronicity.
July 2024 in “Journal of Investigative Dermatology” PRP preparation partially activates platelets, causing varied growth factor release.
July 2024 in “Journal of Investigative Dermatology” Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.
159 citations
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November 2007 in “American Journal of Pathology” In this study, researchers found that substance P triggered premature catagen development and immune changes in human scalp hair follicles, providing a possible biological link between stress and hair loss conditions like telogen effluvium and alopecia areata.
2 citations
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July 1982 in “British Journal of Dermatology” This study reports that retinol acetate inhibited the pro-oxidant effects of benoxaprofen on polymorphonuclear leucocytes in vitro.
April 2026 in “Frontiers in Physiology” This study evaluated nanovesicles derived from Polygonum multiflorum roots, finding that they promote dermal papilla cell proliferation and activate β-catenin signaling, which in turn enhances hair shaft elongation in ex vivo cultured human hair follicles, suggesting their potential use for alopecia treatment.
39 citations
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January 2008 in “World Journal of Gastroenterology” This report documents the first known case of acute inflammatory demyelinating polyneuropathy potentially linked to pegylated interferon-alpha 2a in a woman undergoing treatment for chronic hepatitis C.
March 2024 in “Tissue engineering. Part A” In this study, researchers observed that applying negative pressure to nude mice led to a significant increase in hair follicle growth and angiogenesis, suggesting potential for hair regeneration through mechanisms involving SOX-9, LHX-2, and β-catenin mediation.