June 2022 in “Al-Qadisiyah Journal of Veterinary Medicine Sciences” This study found that 660 nm laser treatment and povidone iodine both eradicated Pseudomonas aeruginosa infection in mice wounds, with the laser enhancing healing, and the combination provided additive or synergistic healing benefits.
Men with early balding may have a higher risk of prostate issues, and surgery for prostate cancer has a slight survival benefit over radiation.
June 2011 in “British Journal of Urology” This review discusses the challenges in developing combination therapies for urological conditions and notes that regulatory requirements and financial disincentives hinder progress, without presenting new clinical findings.
December 2010 in “Médecine des Maladies Métaboliques” The Accu-Chek FlexLink Plus and Accu-Chek LinkAssist Plus make insulin pump use safer, simpler, and more comfortable.
February 2022 in “Journal of Cosmetic Dermatology” In this study, a combination treatment of topical 2% flutamide and 5% minoxidil significantly improved hair density, hair thickness, and patient satisfaction more than 5% minoxidil alone in patients with androgenetic alopecia over six months.
1 citations
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January 2024 in “Updates in clinical dermatology”
63 citations
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March 2001 in “Fertility and Sterility” This study found that Diane 35 combined with finasteride led to a greater reduction in hirsutism scores over 12 months compared to Diane 35 alone.
50 citations
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April 2000 in “Fertility and Sterility” This study found that a combination therapy of Diane 35 with finasteride was more effective at reducing hirsutism scores in women with idiopathic hirsutism or polycystic ovary syndrome after 3 months compared to Diane 35 alone.
47 citations
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March 2004 in “European journal of endocrinology” This study found that the combination of spironolactone and finasteride significantly improved hirsutism scores more than spironolactone alone in women, with similar side-effect profiles between treatments.
36 citations
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June 1990 in “Archives of Dermatology” This study found that combination therapy with 5% minoxidil and 0.5% anthralin led to hair regrowth in some patients with severe treatment-resistant alopecia areata, but also caused mild to moderate irritant dermatitis in all participants.
34 citations
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August 2002 in “British Journal of Dermatology” This study observed that two patients treated with interferon α-2b and ribavirin for chronic hepatitis C experienced complete and reversible straightening of their natural curly hair, which recurred with treatment resumption.
20 citations
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January 2013 in “Evidence-based complementary and alternative medicine” This study found that TGPC plus CGT was more effective than CGT alone in reducing alopecia areata severity in children over 12 months, with similar safety profiles.
17 citations
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August 2002 in “AIDS” This study observed that patients undergoing indinavir/ritonavir therapy for HIV-1 frequently experienced reversible alopecia, likely due to retinoid-like effects, but these were independent of other retinoid-like skin manifestations.
16 citations
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November 2020 in “Research Square (Research Square)” In this study, early treatment with nitazoxanide, ivermectin, or hydroxychloroquine, combined with azithromycin, was associated with reduced hospitalizations, respiratory complications, and deaths in early-stage COVID-19 patients compared to untreated controls.
12 citations
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December 2002 in “Fertility and Sterility” In this study, a combination of spironolactone and finasteride was found to significantly improve hirsutism scores without increasing side effects compared to spironolactone alone.
11 citations
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November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study observed that early treatment with azithromycin and either nitazoxanide, ivermectin, or hydroxychloroquine in COVID-19 patients may reduce viral shedding, symptom duration, and respiratory complications compared to untreated patients.
10 citations
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September 2015 in “Gynecological Endocrinology” In this study, spironolactone and spironolactone plus metformin both significantly reduced hirsutism scores in women with PCOS, but the combination therapy was not more effective than spironolactone alone regarding BMI, hormone levels, or insulin resistance.
9 citations
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July 2022 in “Journal of Clinical Oncology” This study found that oral paclitaxel combined with encequidar improved tumor response rates compared to intravenous paclitaxel in women with metastatic breast cancer, while also reducing neuropathy but increasing certain gastrointestinal and neutropenic side effects.
5 citations
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January 2024 in “Journal of Cancer” In this phase II clinical study, combining anlotinib with standard platinum-based chemotherapy showed promising outcomes and prognosis in treating extensive small-cell lung cancer, with high disease control and response rates.
4 citations
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October 2009 in “International Journal of Endocrinology and Metabolism” This study found that both Diane 35 plus spironolactone and Diane 35 plus finasteride were equally effective and safe for treating hirsutism and acne in Indian women over a 12-month period.
February 2026 in “European journal of medical research” This study found that combination therapy with alpha-adrenergic blockers and 5α-reductase inhibitors significantly improved urinary symptoms, reduced prostate volume, and decreased the risk of acute urinary retention and postoperative surgery in patients with benign prostatic hyperplasia compared to monotherapy.
In an animal study, researchers observed that simvastatin and Luteolin significantly increased hair growth and reduced hair loss in male mice, with improvements linked to their antioxidant and anti-inflammatory properties.
December 2024 in “Asian Journal of Pharmaceutical and Clinical Research” This study found that the combination of platelet-rich plasma with topical minoxidil and finasteride was more effective in treating androgenetic alopecia than the conventional minoxidil and finasteride therapy alone.
January 2024 in “Wiadomości Lekarskie” This review discusses the advantages of robotic hair transplantation using the ARTAS iX robot compared to manual Follicular Unit Extraction, emphasizing enhanced precision, speed, and hair preservation capabilities, and reports no clinical results.
May 2023 in “Metabolites” In this study, adding α-lactalbumin to myo-inositol treatment improved ovulation rates, menstrual cycle duration, and hyperandrogenism in women with PCOS more effectively than myo-inositol alone, suggesting potential benefits for those resistant to inositol treatment.
May 2023 in “Journal of Cosmetic Dermatology” This prospective randomized controlled trial found that combining platelet-rich plasma plus basic fibroblast growth factor injections with topical minoxidil significantly improves hair count and growth rate in androgenetic alopecia patients compared to either treatment alone.
May 2008 in “10th European Congress of Endocrinology” Flutamide alone is as effective as the combination with finasteride for treating hirsutism.
December 2022 in “Plastic and Reconstructive Surgery” In this study, PRPF treatment was more effective than PRP alone in improving hair count and hair quality in androgenetic alopecia patients, with PRPF showing significant improvements in various hair growth parameters and having no statistical differences observed in the placebo group.
March 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” In this study, researchers compared the efficacy of platelet-rich plasma with microneedling versus microneedling alone for treating androgenic alopecia in 50 patients, though results are not reported in the abstract.
January 2021 in “Asian Journal of Research in Dermatological Science”