Straight Hair Associated with Interferon-Alpha Plus Ribavirin in Hepatitis C Infection

    August 2002 in “ British Journal of Dermatology ”
    Didier Bessis, Luong Ms, Pierre Blanc, C Chapoutot, Dominique Larrey, Guilhou Jj, B. Guillot
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    TLDR ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.
    The document describes a study where five retired physicians with chronic X-ray dermatitis were treated using topical 5-aminolaevulinic acid photodynamic therapy (ALA-PDT). Previous treatments such as cryotherapy, and topical antibiotics or corticosteroids had failed to provide relief. ALA-PDT, which involves applying ALA cream to lesions and exposing them to a specific light source, resulted in complete clinical remission for two patients and partial remission for three, with no adverse effects reported. Pain relief was a significant early benefit of the treatment. The study notes the advantages of ALA-PDT, such as low toxicity, minimal side effects, cost-effectiveness, and the potential to prevent surgical interventions. However, the absence of a control group not receiving hyperthermia means the effect of hyperthermia on treatment outcomes is unclear. The document also mentions a retrospective analysis of pemphigus vulgaris in pregnancy, but it is not the primary focus.
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