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research A comparative study of microneedling with PRP plus minoxidil (5%) and minoxidil (5%) alone in androgenetic alopecia
Microneedling with PRP and minoxidil (5%) improves hair growth more than minoxidil (5%) alone.
research A comparative study of microneedling with platelet-rich plasma plus topical minoxidil (5%) and topical minoxidil (5%) alone in androgenetic alopecia
This study found that combining microneedling with PRP and topical minoxidil (5%) significantly improved hair growth in men with androgenetic alopecia compared to using minoxidil alone.
research Clinical and metabolic effects of medroxyprogesterone acetate and ethinyl estradiol plus drospirenone in women with polycystic ovary syndrome
This study found that medroxyprogesterone acetate treatment in women with PCOS reduced hyperandrogenism-related hormonal levels and improved skin conditions without affecting lipid or carbohydrate metabolism.
research The Phenotypic and Genotypic Spectra of Ichthyosis With Confetti Plus Novel Genetic Variation in the 3′ End ofKRT10
This study identified major criteria including ectodermal malformations for diagnosing ichthyosis with confetti, and revealed significant genetic variation in the disease locus within the general population.
research Evaluation of the efficacy of transdermal drug delivery of calcipotriol plus betamethasone versus tacrolimus in the treatment of vitiligo
This study found that microneedling combined with calcipotriol plus betamethasone was more effective in treating vitiligo than microneedling with tacrolimus, particularly in difficult-to-treat areas.
research Biotin and Acetazolamide for Treatment of an Unusual Child With Autism Plus Lack of Nail and Hair Growth
This case report suggests that poor hair and nail growth in children with autism spectrum disorder and developmental delay may indicate a biotin-responsive condition, as biotin and acetazolamide therapy improved symptoms and school performance in the reported patient.
research Efficacy and Tolerability of 6-Month Treatment with Tamsulosin Plus the Hexanic Extract of Serenoa repens versus Tamsulosin Plus 5-Alpha-Reductase Inhibitors for Moderate-to-Severe LUTS-BPH Patients: Results of a Paired Matched Clinical Study
This study found that for men with moderate-to-severe LUTS/BPH, 6 months of treatment with tamsulosin plus the hexanic extract of S. repens was as effective as tamsulosin plus a 5-alpha-reductase inhibitor but had better tolerability.
research DICENTRIC CHROMOSOME 14;18 PLUS TWO ADDITIONAL CNVs IN A GIRL WITH MICROFORM HOLOPROSENCEPHALY AND TURNER STIGMATA
This case report highlights the use of microarray analysis to identify cryptic chromosomal rearrangements in a young woman with intellectual disability and multiple congenital anomalies.
research A comparative study of efficacy of 5% minoxidil and 5% minoxidil plus platelet-rich plasma in same patient for treatment of androgenetic alopecia
This study found that adding platelet-rich plasma to 5% minoxidil treatment improved hair growth outcomes in patients with androgenetic alopecia compared to minoxidil alone.
research COMPARISON OF THERAPEUTIC EFFICACY OF MICRONEEDLING WITH PLATELET-RICH PLASMA PLUS 5% MINOXIDIL AND 5% MINOXIDIL ALONE IN ANDROGENETIC ALOPECIA
This study found that the combination of minoxidil, microneedling, and platelet-rich plasma was more effective for androgenetic alopecia than minoxidil alone, although adverse effects were noted.
research Safety and efficacy of low-dose metronomic cyclophosphamide plus vinorelbine in patients with metastatic breast cancer previously treated with anthracyclines and taxanes.
This study observed that a combination of low-dose cyclophosphamide and vinorelbine appears safe and has promising antitumor activity in patients with metastatic breast cancer resistant to anthracyclines and taxanes, achieving a 44% objective response rate at 6 months with manageable toxicity levels.
research Urological Drug Price Stewardship: Potential Cost Savings Based on the Mark Cuban Cost Plus Drug Company Model
This study suggests that adopting the Mark Cuban Cost Plus Drug Company model for purchasing urological medications could have saved Medicare about $1.29 billion in 2020.
research The Frequency of Metabolic Syndrome is Higher Among PCOS Brazilian Women With Menstrual Irregularity Plus Hyperandrogenism
The study found that among young Brazilian women, the likelihood of metabolic syndrome in those with PCOS is strongly associated with BMI and the phenotype involving menstrual irregularity and hyperandrogenism.
research A Randomized Double-Blind Placebo-Controlled Pilot Trial on the Effects of Testosterone Undecanoate Plus Dutasteride or Placebo on Muscle Strength, Body Composition, and Metabolic Profile in Transmen
This study demonstrated that testosterone treatment increases muscle strength and alters body composition in transmen, and the addition of dutasteride does not impair these anabolic effects.
research The anti-androgen combination, flutamide plus finasteride, paradoxically suppressed LH and androgen concentrations in pregnant spotted hyenas, but not in males
In this study, pregnant spotted hyenas treated with flutamide and finasteride had lower concentrations of several sex hormones, including testosterone and luteinizing hormone, compared to untreated controls.
research Efficacy and Safety of 5% Minoxidil Alone, Minoxidil Plus Oral Spironolactone, and Minoxidil Plus Microneedling on Female Pattern Hair Loss: A Prospective, Single-Center, Parallel-Group, Evaluator Blinded, Randomized Trial
This study found that combining topical minoxidil with microneedling improved hair density more than either minoxidil alone or with spironolactone for women with mild-to-moderate female pattern hair loss.
research Single nucleotide polymorphisms associated with elevated alanine aminotransferase in patients receiving asunaprevir plus daclatasvir combination therapy for chronic hepatitis C
This study found that the CYP3A4 rs4646437 genotype was significantly associated with ALT elevation in Japanese patients undergoing asunaprevir plus daclatasvir therapy for chronic HCV infection, suggesting genotyping may help in monitoring patients safely.
research A Randomised Controlled Single Observer Blinded Study To Determine The Efficacy Of Topical Minoxidil Plus Microneedling Versus Topical Minoxidil In The Treatment Of Androgenetic Alopecia
Combining minoxidil with microneedling leads to better hair regrowth than using minoxidil alone.
research A Randomised Controlled Single Observer Blinded Study To Determine The Efficacy Of Topical Minoxidil Plus Microneedling Versus Topical Minoxidil In The Treatment Of Androgenetic Alopecia
Combining microneedling with minoxidil leads to better hair regrowth than using minoxidil alone.
research BAYONET trial: staged combination with encorafenib, binimetinib, plus cetuximab following encorafenib plus cetuximab for BRAF V600E-mutant metastatic colorectal cancer
The BAYONET trial is a phase II study designed to assess the efficacy and safety of combining encorafenib, binimetinib, and cetuximab for patients with BRAF V600E-mutant metastatic colorectal cancer that is resistant to encorafenib plus cetuximab; results are not yet reported.
research Evaluation of Short-Term Efficacy and Long-Term Oncologi-Cal Outcomes of Different Paclitaxels Plus Platinum Regi-Mens in the Treatment of Serous Ovarian Cancer—A Real World Study
In this observational study, the Liposome-Paclitaxel plus Carboplatin regimen showed better short-term efficacy and comparable long-term outcomes for serous ovarian cancer compared to other regimens.
research [Two drugs have a better outcome. Finasteride plus alpha blocker improves urine flow].
research A randomized controlled, single-observer blinded study to determine the efficacy of topical minoxidil plus microneedling versus topical minoxidil alone in the treatment of androgenetic alopecia
This study found that combining microneedling with topical minoxidil was more effective than minoxidil alone in increasing hair count and improving patient satisfaction for men with androgenetic alopecia, though the cosmetic impact was not significant.
research Analysis of hair follicle penetration of lidocaine and fluorescein isothiocyanate-dextran 4 kDa using hair follicle-plugging method
This study highlights the significance of the hf pathway for the skin permeation of ionized and hydrophilic high molecular compounds, and the usefulness of hf-plugging in evaluating their skin permeability.
research A comparison between finasteride, flutamide, and finasteride plus flutamide combination in the treatment of hirsutism
This study concluded that flutamide alone is more effective than finasteride for reducing hirsutism in women, and the combination of both drugs is not superior to flutamide alone.
research Comparison of Finasteride, Metformin, and Finasteride Plus Metformin in PCOS
This study found that both finasteride and metformin effectively reduced androgen levels and insulin resistance parameters in women with PCOS, without clear evidence of one treatment being superior.
research Promising improvement in infected Wound Healing in Type two Diabetic rats by Combined effects of conditioned medium of human adipose-derived stem cells plus Photobiomodulation
In this study, the combination of conditioned medium from human adipose-derived stem cells and photobiomodulation significantly enhanced wound healing in type 2 diabetic rats compared to using either treatment alone, with particularly superior results in wound strength and new blood vessel formation.
research The mystery of the disinterestedness regard Alopecia areata in Asians (especially Chinese men): A proposal of the use of a synthetic medicament plus a special herb from South America
A synthetic drug and a South American herb may help treat alopecia areata in Chinese men.
research The Density Issue in Hair Transplantation
This study found that mini-micrografting and plug methods achieve comparable hair density, but mini-micrografting requires fewer sessions due to its dense graft packing.