Comparison of Therapeutic Efficacy of Microneedling With Platelet-Rich Plasma Plus 5% Minoxidil and 5% Minoxidil Alone in Androgenetic Alopecia

    June 2025 in “ Journal of Population Therapeutics and Clinical Pharmacology ”
    Harmeet Singh, Minakshi Narah, Krishna Talukdar, Balu Haridas, Porimollika Boruah, Anirban Roy, Pallabi Hatikakoty
    From the encyclopedia
    Minoxidil →

    An essential vasodilator with some anti-androgenic effects

    Microneedling →

    technique to create small wounds in skin to activate collagen production and hair growth

    Platelet-Rich Plasma →

    growth factors taken from your blood and injected into your scalp to stimulate hair

    Image
    Studysummary This study found that the combination of minoxidil, microneedling, and platelet-rich plasma was more effective for androgenetic alopecia than minoxidil alone, although adverse effects were noted. Our plain-language summary of this paper — not a Tressless recommendation.
    The study compared the efficacy of 5% minoxidil alone versus a combination of minoxidil, microneedling, and platelet-rich plasma (PRP) in treating androgenetic alopecia (AGA) in 50 patients aged 18-50. Group B, which received the combination treatment, showed significantly superior outcomes at 6 months compared to Group A, which received only minoxidil. The study found that the combination therapy is more effective, with mild adverse effects such as pruritus, seborrheic dermatitis, and headache. The authors suggest that PRP is a safe and effective adjunct, but recommend further research with standardized protocols and larger studies.
    Discuss this study in the Community →