April 2023 in “Journal of Investigative Dermatology” This literature review evaluates the effectiveness of Platelet-Rich Plasma (PRP) in treating androgenetic alopecia (AGA), a condition affecting over 60% of the global population and responsible for more than 90% of hair loss disorders. The review analyzed 27 controlled studies and clinical trials from 2012 to 2022, involving over 1,072 subjects who received PRP or control treatments bi-monthly to monthly for 3-6 months. The majority of these studies reported positive outcomes, including increased hair growth, density, diameter, and quantity. However, further research is needed to standardize PRP protocols and explore its potential as a combination therapy for optimal AGA treatment.
20 citations,
April 2023 in “The Journal of Urology” This study evaluated the safety and efficacy of platelet-rich plasma (PRP) for treating mild to moderate erectile dysfunction (ED) in a randomized, double-blind, placebo-controlled trial with 61 men. Results showed no significant difference between PRP and placebo groups in achieving a minimum clinically important difference in erectile function at 1 month (58.3% for PRP vs. 53.6% for placebo, P = .730). Both groups had similar improvements in erectile function scores at 1 and 6 months, with no significant differences between them. The study concluded that PRP is safe but not more effective than placebo for improving erectile function in men with mild to moderate ED, highlighting the need for standardized protocols and further research.
2 citations,
February 2021 in “International Journal of Research in Dermatology” Minoxidil with PRP is the best treatment for hair loss.
2 citations,
March 2015 in “Expert opinion on orphan drugs” New treatments for hair loss show promise but need more research to confirm safety and effectiveness.
1 citations,
January 2021 in “European journal of medical and health sciences” The review discussed the potential of Platelet-rich Plasma (PRP) as a treatment for androgenic alopecia (AGA), highlighting its ability to promote hair growth by enhancing angiogenesis and stimulating hair follicle activity. Despite the variability in PRP preparation methods affecting its efficacy, numerous studies, including those by Singhal et al. (2015), Ayatollahi et al. (2017), and Puig et al. (2016), demonstrated PRP's effectiveness in both male and female pattern baldness. The review proposed a treatment protocol involving multiple PRP injections over several months, showing promising results in hair regrowth and patient satisfaction. However, it concluded that further standardized research is needed to optimize treatment protocols and confirm long-term efficacy.
May 2024 in “Journal of the Egyptian Women's Dermatologic Society /Journal of the Egyptian Women's Dermatologic Society” Combining fractional CO2 laser and PRP is very effective for treating female hair loss.
January 2024 in “Journal of Cosmetic Dermatology” Platelet-rich plasma may improve hair density and count in male pattern hair loss, but more high-quality research is needed.
January 2023 in “International Journal of Trichology” PRP therapy for hair loss is safe but its effectiveness is doubtful.
January 2022 in “Springer eBooks” Platelet-rich plasma therapy helps increase hair thickness and slow hair loss.
January 2023 in “Indian Journal of Dermatology, Venereology and Leprology” Higher platelet counts and activators in PRP improve hair density and thickness in treating hair loss.
January 2023 in “Dermatologic Therapy” Intralesional corticosteroids and 5-alpha-reductase inhibitors are the best treatments for frontal fibrosing alopecia.
February 2021 in “Revue médicale de Liège” Platelet-rich plasma injections are a promising new treatment for hair loss, showing initial positive results.
January 2021 in “Skinmed” Platelet-Rich Plasma injections can effectively reduce hair thinning and loss, especially in women.
Platelet-rich plasma injections can effectively reduce hair thinning, especially in women.
48 citations,
January 2017 in “International Journal of Trichology” Microneedling with platelet-rich plasma and minoxidil improves hair growth more than just minoxidil in men with hair loss.
45 citations,
March 2013 in “European Journal of Plastic Surgery” Injecting platelet-rich plasma is a safe and effective way to treat hair loss.
19 citations,
January 2017 in “International Journal of Trichology” The document concludes that injecting platelet-rich plasma can effectively treat androgenetic alopecia, a type of hair loss.
18 citations,
April 2021 in “PLOS ONE” The review concluded that reporting on PRP therapy is often incomplete, leading to uncertainty about its effectiveness.
7 citations,
May 2021 in “Frontiers in Pharmacology” The systematic review and meta-analysis evaluated the efficacy of platelet-rich plasma (PRP) in treating female androgenic alopecia (FPHL) and included 42 studies with 1,569 cases, of which 776 were female participants. PRP showed positive responses and improvements in hair density compared to baseline and placebo, with minimal adverse effects such as mild pain and bruising at injection sites. The study concluded that PRP is a promising treatment for FPHL, though further high-quality randomized controlled trials are needed to confirm its efficacy due to considerable heterogeneity and publication bias.
5 citations,
August 2021 in “Clinics in dermatology” PRP is popular in aesthetic treatments but its effectiveness and safety are still questioned.
5 citations,
January 2020 in “International Journal of Trichology” The study compared microneedling (MN) alone versus microneedling with platelet-rich plasma (PRP) in treating male pattern alopecia in 30 male patients using a split-head design. Both treatments significantly increased hair thickness and density, with MN alone showing a greater increase in thickness and MN + PRP showing a greater increase in density. However, the differences were not statistically significant. Both treatments were effective, safe, and well-tolerated, but PRP did not provide additional benefits over MN alone. The study was limited by its small sample size and lack of long-term follow-up.
2 citations,
April 2014 in “PubMed” Platelet Rich Plasma (PRP) shows promise for hair growth, ulcer healing, and skin rejuvenation, but more research is needed for consistent results and it's not suitable for people with certain blood conditions.
1 citations,
October 2021 in “Cureus” Platelet-rich plasma treatment may safely and effectively reduce skin lesions in psoriasis and atopic dermatitis.
1 citations,
October 2021 in “QJM: An International Journal of Medicine” This study compared the efficacy of single-spin versus double-spin platelet-rich plasma (PRP) injections in treating female pattern hair loss (FPHL) in 15 female patients. Each patient received double-spin PRP on one half of the scalp and single-spin PRP on the other half, with three treatment sessions spaced three weeks apart. Results showed significant improvement in hair density on the side treated with double-spin PRP, as evidenced by patient photographs and folliscopic assessments. However, the concentration of vascular endothelial growth factor (VEGF) did not significantly differ between the two PRP preparations, nor did it increase with calcium activation. The study concludes that double-spin PRP may be more effective for FPHL treatment than single-spin PRP, but further research with larger sample sizes is needed to refine PRP preparation methods.
June 2024 in “International Journal of Research in Dermatology” Combining PRP and minoxidil is more effective for hair loss than using either alone.
June 2024 in “Journal of Cosmetic Dermatology” PRP shows promise for hair growth, but more research and standardized protocols are needed.
February 2024 in “Journal of cutaneous and aesthetic surgery” The combined treatment helps improve severe hair loss and reduces the need for other medications.
January 2024 in “JCPSP. Journal of the College of Physicians & Surgeons Pakistan” PRP therapy is more effective than minoxidil for treating hair loss from androgenetic alopecia.
June 2023 in “Journal of Cosmetic Dermatology” The treatment combining platelet-rich plasma and a non-cross-linked hyaluronic acid compound significantly improved hair density and reduced bald areas in women with androgenetic alopecia, and it's safe with only mild side effects.
June 2023 in “Journal of cosmetic dermatology” Both DPCP alone and with PRP are effective and safe for treating severe alopecia areata.