November 2025 in “American Journal of Tropical Medicine and Hygiene” In this study, researchers observed that approximately 1.15% of dengue fever patients experienced alopecia, predominantly among females. The hair loss usually occurred during the recovery phase and was often identified as telogen effluvium, with lower platelet count and hematocrit levels potentially serving as risk factors.
March 2024 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that platelet-rich plasma therapy may effectively improve hair density and related parameters in men with androgenetic alopecia, with results differing based on specific platelet counts.
December 2023 in “PubMed” This study found that both single- and double-spin PRP preparation methods significantly increased thrombocyte counts and improved hair parameters in males with androgenetic alopecia, with the single-spin method showing a more significant increase in thrombocyte count.
January 2023 in “Indian Journal of Dermatology, Venereology and Leprology” In this study, activated platelet-rich plasma improved hair density and thickness in patients with androgenetic alopecia, with higher platelet counts enhancing these effects over time.
January 2021 in “Turkiye Klinikleri Journal of Dermatology” In this study, the MPV/PC ratio was identified as a potential tool for assessing disease activity in alopecia areata, with higher ratios in active and severe cases compared to inactive and mild/moderate ones.
July 2025 in “Journal of Dermatological Treatment” This study found that platelet-rich plasma significantly improved hair growth parameters in androgenic alopecia patients and was even more effective when combined with minoxidil, particularly in reducing vellus hair.
June 2024 in “Clinical and Experimental Obstetrics & Gynecology” In this study, women with recurrent implantation failure after IVF/ICSI had significantly lower platelet, plateletcrit, and lymphocyte counts, but these parameters were not effective for predicting the condition.
214 citations
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September 2015 in “Stem Cells Translational Medicine” This study found that platelet-rich plasma injections significantly increased hair count and density in patients with male pattern hair loss without major side effects, suggesting it may be a safe and effective treatment option.
69 citations
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April 2019 in “Biomedicines” This study found that hair thickness and density increased after treatment with human follicle mesenchymal stem cells and platelet rich plasma, associated with enhanced Wnt signaling and platelet derived growth factors.
18 citations
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January 2019 in “International Journal of Trichology” This study found that PRP therapy resulted in better hair growth and patient satisfaction than minoxidil therapy in men with androgenetic alopecia over six months, and patients with higher platelet counts in PRP experienced greater improvement.
2 citations
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March 2023 in “Biomedicine & pharmacotherapy” This study found that platelet lysate significantly improved hair growth and follicle performance in both experimental settings and AGA patients, showing results comparable to platelet-rich plasma.
2 citations
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June 2021 in “Cosmoderma” This article reviews the use of platelet-rich plasma (PRP) in various dermatological conditions and reports no new clinical results; the authors emphasize its efficacy and call for continued careful use.
This chapter reviews the combined use of platelet-rich plasma and microneedling for cosmetic enhancement but reports no clinical results; the authors highlight existing uses and suggest potential synergistic benefits in dermatology.
1 citations
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November 2020 in “Journal of The American Academy of Dermatology” This study highlights criticisms of existing research on PRP as a treatment for androgenetic alopecia, noting small sample sizes, lack of controls, subjective result analysis, and varied methodologies.
June 2020 in “Journal of Investigative Dermatology” This study found that FDA-cleared devices for preparing platelet-rich plasma showed inconsistent product quality, with variable platelet counts and inadequate quality control performance, suggesting clinical improvement may not rely on platelet concentration.
April 2026 in “Mathematics” This study used a probabilistic framework to show that platelet-rich plasma preparation results in significant variability in platelet dose due to factors like injected volume and concentration factor.
September 2017 in “Springer eBooks” PRP injection therapy shows promise for treating hair loss, increasing hair count and thickness with minimal side effects.
January 2023 in “Journal of Cosmetic Dermatology” This review concludes that platelet-rich plasma treatment is effective for androgenetic alopecia, with recommendations for a specific volume, frequency, and duration of therapy for optimal results.
3 citations
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February 2023 in “International Journal of Molecular Sciences” This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.
183 citations
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January 2014 in “BioMed Research International” This study reported that AA-PRP injections significantly increased hair count and density in individuals with pattern hair loss compared to baseline, demonstrating their potential for enhancing hair growth.
115 citations
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January 2014 in “Journal of Cutaneous and Aesthetic Surgery” In this study, PRP injections increased hair count and reduced hair loss in patients with androgenic alopecia not responding to minoxidil and finasteride, with high patient satisfaction reported.
87 citations
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September 2016 in “Dermatologic Surgery” This study found that platelet-rich plasma did not significantly improve hair mass index or hair count in women with female androgenetic alopecia, though some patients perceived benefits in hair quality.
74 citations
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January 2015 in “Asian Journal of Transfusion Science” This study found that platelet-rich plasma injections led to improvements in hair counts, thickness, and strength in patients with androgenic alopecia, showing promise as an effective treatment with no major adverse effects.
66 citations
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June 2015 in “Aesthetic Plastic Surgery” This review of 47 studies indicates that platelet preparations may significantly enhance cellular activity, wound healing, and facial aesthetic outcomes in facial plastic surgery, though potential publication bias should be considered.
39 citations
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July 2021 in “Stem Cell Research & Therapy” This study found that combining platelet-rich plasma with adipose-derived mesenchymal stem cells significantly improved diabetic wound healing in rats by enhancing angiogenesis and modulating the Notch signaling pathway.
23 citations
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June 2018 in “Facial Plastic Surgery” This review suggests that platelet-rich plasma is a low-risk treatment for androgenic alopecia with good patient satisfaction and positive objective outcomes, but further research is needed to refine methods and standardize outcome measurements.
12 citations
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May 2019 in “Aesthetic Surgery Journal” This review highlights new treatment options for hair restoration, including platelet-rich plasma and stem cell therapy, which have shown efficacy in increasing hair count and density for androgenetic alopecia and alopecia areata, but presents no original clinical data.
3 citations
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June 2017 in “PubMed” In this study, autologous platelet-rich plasma prepared with Merisis One Step Gel Separation Technology improved hair counts, thickness, root strength, and overall alopecia in five patients without major adverse effects over three months.
2 citations
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July 2019 in “Journal of The American Academy of Dermatology” This letter raises questions for the authors of a recent study on platelet-rich plasma for androgenetic alopecia, without presenting new clinical results.
1 citations
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December 2023 in “PubMed” This study on rats found that combining platelet-rich plasma with stromal vascular fraction cells helped accelerate burn wound healing by affecting inflammatory cell counts and COX-2 expression, with differing impacts observed between acute and sub-acute phases of healing.