Evaluation of Some Biochemical Markers in Alopecia Areata
January 2023
in “
International journal of dermatology, venereology and leprosy sciences
”
New to Alopecia Areata? There is a guide in the encyclopedia. Read the guide → 
Studysummary This study found that patients with alopecia areata had altered levels of inflammatory and coagulation markers, suggesting an association with disease pathogenesis and potential predictive value.
Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
The study "Evaluation of some biochemical markers in alopecia areata" involved 25 patients with alopecia areata (AA) and 25 healthy individuals. The researchers found that AA patients had significantly lower mean corpuscular hemoglobin (MCH) and platelet counts, and higher white blood cell (WBC) counts, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), D-dimer, and thyroid stimulating hormone (TSH) levels. These markers were found to be predictive of the disease occurrence. CRP and D-dimer levels showed the best diagnostic performance with sensitivities of 92% for both, and specificities of 80% and 76%, respectively. The study concluded that there is an association between coagulation system dysfunction, acute inflammatory state, and autoimmune reactions in AA.
