Assessment of the Mean Platelet Volume-to-Platelet Count Ratio in Alopecia Areata: A Retrospective Case Control Study

    January 2021 in “ Turkiye Klinikleri Journal of Dermatology ”
    Gül Aslıhan ÇAKIR AKAY, Burcu Tuğrul
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    TLDR The MPV/PC ratio can help assess disease activity in alopecia areata.
    The study evaluated the mean platelet volume (MPV), platelet count (PC), and MPV/PC ratio in 75 patients with alopecia areata (AA) compared to 70 healthy controls. Results showed that AA patients had significantly lower PC and MPV values, and a higher MPV/PC ratio. The MPV/PC ratio was notably higher in active and severe AA cases. The study concluded that the MPV/PC ratio could be a practical marker for assessing disease activity in AA, with a cut-off value of 0.036, sensitivity of 52.0%, and specificity of 85.7%.
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