Assessment of the Mean Platelet Volume-to-Platelet Count Ratio in Alopecia Areata: A Retrospective Case Control Study

    January 2021 in “ Turkiye Klinikleri Journal of Dermatology ”
    Gül Aslıhan ÇAKIR AKAY, Burcu Tuğrul
    Image of study
    TLDR The MPV/PC ratio can help assess disease activity in alopecia areata.
    The study evaluated the mean platelet volume (MPV), platelet count (PC), and MPV/PC ratio in 75 patients with alopecia areata (AA) compared to 70 healthy controls. Results showed that AA patients had significantly lower PC and MPV values, and a higher MPV/PC ratio. The MPV/PC ratio was notably higher in active and severe AA cases. The study concluded that the MPV/PC ratio could be a practical marker for assessing disease activity in AA, with a cut-off value of 0.036, sensitivity of 52.0%, and specificity of 85.7%.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 1000+ results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community When are we getting a cure to hair loss?

      in Chat 2 years ago
      Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 11 months ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community To my fellow under 20s that are balding

      in Chat  127 upvotes 2 years ago
      The conversation is about young men under 20 experiencing hair loss. They discuss their experiences and treatments used, including finasteride (fin) and minoxidil (min).

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 3 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

    Related Research

    3 / 3 results