TLDR The MPV/PC ratio can help assess disease activity in alopecia areata.
The study evaluated the mean platelet volume (MPV), platelet count (PC), and MPV/PC ratio in 75 patients with alopecia areata (AA) compared to 70 healthy controls. Results showed that AA patients had significantly lower PC and MPV values, and a higher MPV/PC ratio. The MPV/PC ratio was notably higher in active and severe AA cases. The study concluded that the MPV/PC ratio could be a practical marker for assessing disease activity in AA, with a cut-off value of 0.036, sensitivity of 52.0%, and specificity of 85.7%.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
95 citations,
November 2018 in “Australasian journal of dermatology” Alopecia areata treatment varies, with no optimal method established yet.
65 citations,
April 2016 in “Experimental dermatology” Corticosteroid treatment reduces inflammation and alters hair keratins in alopecia areata.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
4 citations,
November 2018 in “JAAD case reports” Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.
