68 citations,
December 2014 in “Cell Biochemistry and Function” Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
127 citations,
June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
20 citations,
October 2018 in “Aesthetic Plastic Surgery” PRP shows promise for improving facial wrinkles, skin elasticity, and hair growth, but more research is needed to standardize its use and understand its effects.
306 citations,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.
6 citations,
January 2022 in “Journal of Investigative Dermatology” Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.
2 citations,
December 2023 in “Advanced science” Glycosaminoglycans help heal wounds but aren't yet ready for clinical use.
19 citations,
November 2011 Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
212 citations,
May 2012 in “Genes & Development” Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
12 citations,
May 2019 in “Molecular Medicine Reports” Forsythiaside A helps reduce brain damage from lack of blood flow by activating certain protective pathways.
91 citations,
July 2010 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
77 citations,
January 1980 in “Carcinogenesis” TPA is about 50 times more effective at promoting tumors than MZ.
Icosapent ethyl may help treat long-lasting symptoms after COVID-19.
18 citations,
June 1998 in “Circulation” Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.
91 citations,
December 2017 in “Systems Biology in Reproductive Medicine” Lower SHBG levels may increase the risk of PCOS.
7 citations,
July 2013 in “International Journal of Dermatology” No link found between Coxsackie viruses and pemphigus.
44 citations,
July 2011 in “Dermato-endocrinology” Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
11 citations,
October 2018 in “Nucleic Acid Therapeutics” Modified KGF mRNA helps skin cells grow and move faster, which may improve wound healing.
January 2008 in “Springer eBooks” Thyroid hormone may be useful for treating various skin conditions and needs more research.
8 citations,
July 2022 in “BMC neuroscience” Transplanted hair follicle stem cells improved brain function and reduced damage after a stroke in rats.
24 citations,
July 2011 in “PubMed” Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
13 citations,
January 2020 in “Scientific Reports” The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
11 citations,
July 2012 in “Experimental dermatology” Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
224 citations,
February 2013 in “The Journal of clinical investigation/The journal of clinical investigation” ERG increases SOX9, promoting prostate cancer growth and invasion.
3 citations,
October 2011 in “QJM” The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.
5 citations,
August 2013 in “InTech eBooks” KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
January 2019 in “Springer Reference Medizin” Follicle Stimulating Hormone is important for fertility.
November 2022 in “Orphanet Journal of Rare Diseases” Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.
November 2008 in “Medical & surgical dermatology” A device was made in 2008 to measure hair loss severity. Other findings include: frizzy mutation in mice isn't related to Fgfr2, C/EBPx marks preadipocytes, Cyclosporin A speeds up hair growth in mice, blocking plasmin and metalloproteinases hinders healing, hyperbaric oxygen helps ischemic wound healing, amniotic membranes heal wounds better than polyurethane foam, rhVEGF165 from a fibrin matrix improves tissue flap viability and induces VEGF-R2 expression, and bFGF enhances wound healing and reduces scarring in rabbits.
January 2000 in “Expert Opinion on Therapeutic Patents” The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.