October 2024 in “International Journal of Research in Dermatology” This study reported that using Mintop Pro+ hair regrowth serum twice daily for 90 days significantly reduced hair fall and increased consumer satisfaction with hair growth and density, without any adverse events, among 161 participants aged 18-55 years with hair loss concerns.
January 2023 in “Pakistan Armed Forces Medical Journal”
February 2021 in “Dermatologic Therapy” This study concluded that intralesional lyophilized growth factor injections are safe and improve trichoscopic hair parameters and clinical scores in patients with female pattern hair loss.
October 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Adding dalteparin and protamine microparticles to platelet-rich plasma can boost hair growth more than using platelet-rich plasma alone.
January 2013 in “프로그램북(구 초록집)” This study found that sequential treatment with platelet-rich plasma injection followed by mesotherapy may promote hair growth in various alopecia cases, showing clinical improvement in hair count and thickness.
January 2024 in “Journal of Education, Health and Sport” This review discusses the modern production methods, mechanisms of action, and various uses of platelet-rich plasma in medicine, highlighting promising applications but noting the need for more high-quality research.
September 2022 in “Open Access Macedonian Journal of Medical Sciences” This review discusses the application of platelet-rich plasma in cosmetic dermatology for tissue regeneration, wound healing, and alopecia treatment, but it reports no new clinical results.
20 citations
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July 2019 in “Stem cell investigation” This study found that the combination of stromal vascular fraction and platelet-rich plasma accelerated wound healing in rats more effectively than either treatment alone or saline.
2 citations
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March 2017 in “Current regenerative medicine” This article reviews the use of platelet rich plasma in regenerative medicine and highlights the need for standardization in its preparation and application, reporting no new clinical results.
11 citations
,
May 2021 in “Journal of Cosmetic Dermatology” This review discusses the potential use of platelet-rich plasma for treating melasma, suggesting its effectiveness but noting the need for more extensive studies to confirm these findings.
3 citations
,
November 2022 in “Frontiers in molecular biosciences” This study suggests that in mice, plasmalogens may enhance hair growth by activating TRPC4 channels, which increases calcium influx and subsequently stimulates AMPK in hair follicles.
25 citations
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September 2019 in “PubMed” This review discusses the therapeutic potential of platelet-rich plasma in dermatology and highlights the need for standardized treatment protocols, but reports no new clinical results.
2 citations
,
June 2019 in “Serbian Journal of Dermatology and Venereology/Serbian Journal of Dermatology and Venerology” This study reported remarkable improvement in three patients with treatment-resistant alopecia areata after receiving autologous platelet-rich plasma injections, suggesting the potential for this approach and a need for further randomized, placebo-controlled trials.
January 2024 in “Journal of Scleroderma and Related Disorders” This study concluded that autologous platelet-rich plasma is a safe and effective technique for improving aesthetic concerns such as contour defects, pigmentation issues, and indurated lesions.
169 citations
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January 2020 in “Burns & Trauma” In this study, autologous platelet-rich plasma improved skin wound healing in mice, associated with reduced inflammation and enhanced angiogenesis and re-epithelialization, but the underlying regulatory mechanism requires further investigation.
August 2024 in “Quality in Sport” This review highlights the positive effects of platelet-rich plasma in aesthetic and regenerative medicine, particularly for skin rejuvenation, anti-aging, hair reconstruction, and wound healing, but it reports no new clinical results.
1 citations
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November 2021 in “European journal of medical and health sciences” In three patients with diabetic ulcers, this study reported remarkable wound healing and tissue regeneration after 3 to 6 weekly applications of growth factors-rich plasma and membrane treatment.
July 2024 in “Dermatological Reviews” This review discusses the potential benefits of PRP, exosomes, and stem cells in aesthetic medicine, noting the challenges in interpreting study results due to the lack of standardized protocols.
29 citations
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March 2016 in “Dermatologic therapy” In this study, a patient with lichen planopillaris experienced complete resolution of itching and hair shedding following treatment with a new platelet-rich plasma regimen, marking the first reported success in this context.
1 citations
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May 2024 in “Skin Appendage Disorders” In this case study, researchers reported that a patient with plaque alopecia areata experienced complete and sustained hair regrowth after treatment with 5-Fluorouracil and Bleomycin via microinfusion of medicines, despite initial cutaneous atrophy caused by intralesional corticosteroid therapy.
December 2021 in “Journal of clinical images and medical case reports” This review compares mesotherapy and PRP for hair loss but reports no new clinical results; the authors highlight the need to understand their differences for optimal treatment choices.
This study found that intrathyroidal injection of autologous platelet-rich plasma improved thyroid function and symptoms in hypothyroidism patients, without adverse events over one year.
3 citations
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January 2024 in “Cell Transplantation” This study reviews various factors affecting mesenchymal stem cell transplantation efficacy, including platelet concentrate composition, donor characteristics, and environmental influences, and examines strategies for optimizing outcomes through preconditioning and combined therapies in regenerative medicine.
2 citations
,
January 2024 in “Journal of Personalized Medicine” This study found that combining adipose-derived mesenchymal stem cells with platelet-rich plasma improved key healing markers in bowel anastomoses in rats with induced colitis, suggesting potential benefits for anastomosis recovery even in inflamed conditions.
4 citations
,
January 2022 in “Transfusion Medicine and Hemotherapy” This review discusses the varied applications of platelet-rich plasma in plastic surgery and reports mixed evidence on its efficacy, indicating a need for more standardized, controlled trials.
September 2024 in “Journal of the American Academy of Dermatology” This review discusses the limited evidence on the efficacy of platelet-rich plasma for treating endocrine therapy-induced and permanent chemotherapy-induced alopecia and reports no new clinical results.
4 citations
,
October 2020 in “JAAD Case Reports” This article discusses the potential use of platelet-rich plasma as a treatment for vitiligo, but reports no new clinical results; further investigation is needed.
4 citations
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May 2014 in “Journal of Cutaneous Medicine and Surgery” Platelet-rich plasma may help with wound healing, hair growth, and skin rejuvenation, but more research is needed to prove its effectiveness.
1 citations
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December 2023 in “PubMed” This study on rats found that combining platelet-rich plasma with stromal vascular fraction cells helped accelerate burn wound healing by affecting inflammatory cell counts and COX-2 expression, with differing impacts observed between acute and sub-acute phases of healing.
19 citations
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December 2020 in “Plastic and Reconstructive Surgery” This article reviews the use of platelet-rich plasma for skin rejuvenation and hair regrowth, noting positive outcomes despite variability in preparation and a lack of standardized protocols.