33 citations
,
July 2020 in “Journal of The American Academy of Dermatology” In this study, PRP increased hair density in areas treated for androgenetic alopecia, but there was no significant difference when compared to placebo-treated areas.
45 citations
,
August 2019 in “Dermatologic Therapy” This review discusses the physiopathology of androgenetic alopecia and evaluates various traditional and emerging treatments, reporting no new clinical results but highlighting the need for enhanced treatment strategies.
19 citations
,
June 2019 in “Clinical Drug Investigation” This study concluded that platelet-rich plasma injections significantly improved hair density, thickness, and scalp inflammation in both male and female pattern hair loss, with better outcomes in lower-grade cases.
27 citations
,
June 2019 in “Aesthetic Plastic Surgery” Platelet-Rich Plasma (PRP) treatment may increase hair growth for genetic hair loss, but more research is needed to confirm this.
11 citations
,
January 2019 in “International Journal of Trichology” This study observed no significant improvement of mesotherapy over 5% topical minoxidil for male androgenic alopecia, despite a small increase in hair shaft diameter variation with mesotherapy.
6 citations
,
October 2018 in “Dermatologic Surgery” This abstract does not present new clinical findings or a research study.
57 citations
,
October 2018 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma significantly increased hair count, density, and the percentage of anagen hairs in patients with androgenetic alopecia, but these improvements did not correlate with platelet or growth factor levels.
16 citations
,
July 2018 in “Dermatologic Surgery” In this study, iL-PRF injections produced significantly better clinical scores for androgenetic alopecia patients compared to controls, especially in those with more severe baseline conditions.
16 citations
,
January 2018 in “Dermatology Online Journal” This review discusses platelet-rich plasma treatment for androgenic alopecia, summarizing current understanding of the disease and the need for standardized clinical trials, but it reports no new results.
52 citations
,
May 2017 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma injections significantly improved hair density, thickness, and patient satisfaction in women with female pattern hair loss compared to a placebo.
153 citations
,
March 2017 in “Endocrine” This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
70 citations
,
February 2017 in “Dermatologic Surgery” This study reports that plasma rich in growth factors appeared to improve hair follicle regeneration and patient satisfaction in individuals with androgenetic alopecia, though further trials are needed.
136 citations
,
February 2017 in “International Journal of Molecular Sciences” This study observed that autologous platelet-rich plasma treatment improved hair count and density in areas with androgenetic alopecia compared to placebo, with differing outcomes based on the PRP collection device used.
27 citations
,
January 2017 in “Indian Dermatology Online Journal” This study found no significant benefit from PRP injections for treating androgenetic alopecia in men, highlighting the need for larger, well-designed trials to assess its effectiveness and safety.
33 citations
,
January 2017 in “Journal of Cutaneous and Aesthetic Surgery” This study found that PRP injections improved hair density, quality, and thickness in males with androgenic alopecia compared to placebo, with reported high patient satisfaction and no major side effects.
60 citations
,
September 2016 in “Dermatologic Surgery” This article proposes a mechanistic model for how platelet-rich plasma therapy may stimulate hair growth in androgenetic alopecia by promoting vascularization and activating specific signaling pathways, but it reports no new experimental results.
87 citations
,
September 2016 in “Dermatologic Surgery” This study found that platelet-rich plasma did not significantly improve hair mass index or hair count in women with female androgenetic alopecia, though some patients perceived benefits in hair quality.
61 citations
,
September 2016 in “Journal of Cosmetic and Laser Therapy” This study found that platelet-rich plasma was not effective in treating androgenetic alopecia in men with grade 4–6 hair loss.
136 citations
,
April 2016 in “Dermatologic Surgery” This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.
14 citations
,
January 2016 in “International Journal of Trichology” This study observed that many female pattern hair loss patients had concurrent conditions such as telogen effluvium, hypothyroidism, and hypertension, with a significant percentage having low Vitamin D levels.
214 citations
,
September 2015 in “Stem Cells Translational Medicine” This study found that platelet-rich plasma injections significantly increased hair count and density in patients with male pattern hair loss without major side effects, suggesting it may be a safe and effective treatment option.
91 citations
,
August 2015 in “Anais Brasileiros De Dermatologia” This review discusses the clinical, epidemiological, and pathophysiological aspects of female pattern hair loss, reporting no new research findings.
107 citations
,
August 2014 in “Dermatologic Surgery” This pilot study suggests injecting platelet-derived growth factors into the scalp may offer some clinical benefits for androgenetic alopecia, though further randomized trials are needed for confirmation.
183 citations
,
January 2014 in “BioMed Research International” This study reported that AA-PRP injections significantly increased hair count and density in individuals with pattern hair loss compared to baseline, demonstrating their potential for enhancing hair growth.
164 citations
,
January 2014 in “Journal of Cutaneous and Aesthetic Surgery” This study found that PRP injections may improve hair density and reduce hair loss in patients with androgenetic alopecia without significant side effects, but further research is needed to confirm efficacy.
36 citations
,
December 2012 in “Dermatologic Surgery” Injecting platelet-rich plasma (PRP) can increase hair growth rate and density in male pattern baldness.
32 citations
,
November 2012 in “Aesthetic Surgery Journal” This article reviews advancements in hair restoration, highlighting improvements in surgical techniques and patient satisfaction, but reports no new clinical results.
42 citations
,
June 2009 in “Journal of Cosmetic Dermatology” In this study, researchers observed that follicular microinflammation significantly contributes to the early stages of male androgenetic alopecia, potentially leading to perifollicular fibrosis and follicle destruction as the condition progresses.
28 citations
,
August 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified that survivin is expressed in human hair follicles during their growth phase and its expression may be regulated by Wnt/β-catenin signaling, potentially influencing the balance between cell proliferation and apoptosis in hair follicle cycles.
229 citations
,
August 2002 in “Experimental Gerontology” This paper discusses key mechanisms of androgen metabolism in androgenetic alopecia and reports the effectiveness of treatments like oral finasteride and topical minoxidil, highlighting the limited success rate due to factors like follicular inflammation.