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This study suggests that PKCß plays a critical role in modulating the dermal inflammatory microenvironment in response to dietary lipids in mice.

The researchers reported that disrupting the RPGRIP1L gene in mice impaired desmosome function, causing skin blistering, and their findings suggest that PKCβII inhibition could help treat pemphigus.

This study found that anthralin and sodium dodecyl sulfate accelerated hair growth in mice, potentially involving different skin protein kinase C isoform responses.

This study found that inhibiting PKC-β activity with bisindolylmaleimide reduces pigmentation in the skin and hair of guinea pigs and mice by preventing tyrosinase activation.

This study found that thymosin beta-4 overexpression in mice increased hair growth speed and density, likely by regulating P38/ERK/AKT signaling through VEGF expression.

This study found that in a mouse model of Leigh syndrome, rapamycin alters brain proteome and may extend survival by targeting protein kinase C.

This review evaluates existing research on Keratin 15 to assess its validity as a marker for epidermal stem cells, reporting no new results.

This review discusses the roles of Wnt signaling in skin organogenesis and related processes but reports no new experimental results, highlighting areas for future research.

This study found that procyanidin B-3, a compound isolated from barley extract, may promote hair growth by enhancing hair epithelial cell growth and counteracting TGF-β1's growth-inhibiting effects in vitro and in vivo.

This study suggests that Keratin 15 expression in stratified epithelia may be regulated by two distinct mechanisms involving PKC/AP-1 pathway for differentiation and FOXM1 for basal cells, challenging its reliability as a sole stem cell marker.

This review discusses the developmental regulation of wound healing mechanisms in mammals, focusing on the role of the Wnt and TGF‐β signaling pathways, and reports no new clinical findings.

This review discusses the role of lysophosphatidic acid in skin physiology and pathology, highlighting its significance in processes like wound healing and hair follicle development, but reports no new clinical findings.

This study found that procyanidin oligomers from apples and barley may stimulate hair growth by promoting hair epithelial cell proliferation and protecting them from apoptosis via MEK activation in a murine model.

This study found that Euph E and Euri A showed strong anti-inflammatory activity and modulated cytokine and immune functions in macrophages, related to specific signaling pathways.

This review discusses the similarities between wound healing and embryonic development, focusing on signaling pathways and their potential for developing new wound healing strategies, and reports no new clinical results.

In this study, the researchers found that vitamin D and calcium signaling in keratinocytes are essential for normal skin regeneration after wounding, with deficiencies significantly delaying wound closure and re-epithelialization in mice.

In this study, researchers discovered that ROR2, a Wnt receptor, plays a crucial role in regulating hair follicle stem cell self-renewal and maintenance, compensating for the absence of β-catenin.

This review discusses how vitamin D and calcium signaling are essential for wound healing by activating epidermal and hair follicle stem cells, noting that deficiencies may lead to delayed or chronic wounds.

In this clinical study, researchers reported that both sodium valproate-loaded nanospanlastics and topical corticosteroids showed comparable modest efficacy in treating patchy alopecia areata, recommending further investigation into sodium valproate's role combined with other therapies.

This review discusses the conserved molecular mechanisms controlling hair follicle development and cycling and suggests they may also apply to other ectodermal derivatives, like teeth and feathers, but it reports no new results.

This review explores embryonic epidermal development and discusses key molecular regulators and roles of the sub-epidermal mesenchyme, but reports no new experimental results.

This study found that proteins secreted by early-passage dermal papilla cells, including SDF1, MMP3, biglycan, and LTBP1, may play significant roles in hair follicle regeneration.

This study found that ethanol extract and an ethyl acetate fraction of Sargassum fusiforme promoted hair regrowth in C57BL/6 mice and stimulated expression of hair growth-related genes in both in vitro and in vivo models.

This review discusses the role of corticotropin-releasing hormone in human skin, focusing on its regulation, receptors, and functions, and highlights parallels with the hypothalamo-pituitary-adrenal axis; it reports no new research findings.

In this study, researchers used a mouse model to demonstrate that expression of MARCKSL1 in dendritic cells plays a crucial role in modulating fibrotic responses and scar formation during wound healing, suggesting that targeting this expression could offer new therapeutic strategies for scar prevention.

This review discusses the regulation of involucrin gene expression, focusing on transcription factors and signaling pathways, and reports no new experimental findings.

This study found that BMP-2 activates Dlx3 gene transcription in murine keratinocytes by binding with Smad1/Smad4, suggesting a mechanism for BMP signaling's role in skin and hair follicle regulation.

The authors reported that 4-O-methylhonokiol decreased TGF-β1-induced cell cycle arrest and oxidative stress markers in human keratinocyte cells, suggesting a potential protective role in TGF-β1-mediated cell cycle regulation.

This review discusses the potential carcinogenic effects of anabolic androgenic steroids, particularly regarding Leydig cell tumors, and highlights the need for preventive information campaigns due to associated health risks.

This review discusses vitamin D and calcium signaling roles in epidermal stem cell processes essential for wound healing but reports no new experimental results, emphasizing their potential interdependent regulatory mechanisms.