PKCδ/MAPKs and NF-κB Pathways Involved in Regulation of Ingenane-Type Diterpenoids from Euphorbia Neriifolia on Macrophage Function
June 2021
in “
Journal of Inflammation Research
”
TLDR Euph E and Euri A from Euphorbia neriifolia help control inflammation and immune response in cells.
The study demonstrated that Euph E and Euri A, ingenane-type diterpenoids from Euphorbia neriifolia, exhibited multidirectional regulation on cytokines and immune function of macrophages, along with notable anti-inflammatory activity. This regulation was closely associated with the PKCδ/MAPKs and NF-κB signaling pathways.