September 2020 in “Oral surgery, oral medicine, oral pathology and oral radiology” This case report describes a pilomatricoma in a 21-year-old woman, highlighting the diagnostic process and illustrating the potential for intraoral surgical access to minimize scarring.
88 citations
,
June 2000 in “Journal of Investigative Dermatology” Keratin 17 is important for hair and nail structure and affects pachyonychia congenita symptoms.
January 2026 in “Food and Nutrition Sciences” This randomized, placebo-controlled trial reported that USPlus PRO saw palmetto extract significantly improved lower urinary tract symptoms, including voiding, incomplete emptying, and weak stream, as well as sexual function in males over 12 weeks, while maintaining a favorable safety profile.
This study found that PLX, a mixture of tomato extract and chitooligosaccharide, may reduce prostate weight in testosterone-induced BPH in rats, suggesting it could act as a 5α-reductase inhibitor.
September 2023 in “International journal of biological macromolecules” This study found that a chitosan/PDRN nanopolyplex significantly improved diabetic wound healing in rats by enhancing cell proliferation, migration, and antimicrobial activities, suggesting its potential as a therapeutic product.
This review examines complex regional pain syndrome (CRPS I) mechanisms, including immune dysregulation and psychological factors, but reports no new clinical results; the authors highlight potential diagnostic refinements.
This study investigated the molecular mechanisms behind the formation of drug-polymer inclusion complexes and found that carbamazepine can self-assemble into stable channel structures without guest polymers, unlike griseofulvin, which requires guest molecules for structural stability.
13 citations
,
November 1985 in “International Journal of Dermatology” This study examined patients with trichostasis spinulosa and identified distinct differences in the distribution and microscopic appearances of lesions compared to keratosis pilaris and eruptive vellus hair cysts.
10 citations
,
January 2010 in “International journal of trichology” This study found that keratin-associated proteins form part of the developing exocuticle and a-layer in hair fiber cuticle cells, while cornified envelope proteins were absent.
11 citations
,
January 1997 in “Journal of Dermatological Science” This study identified a human sequence likely coding for a new ultra-high sulphur protein, which may aid in understanding hair differentiation and the molecular basis of human trichothiodystrophy.
July 2021 in “Journal of dermatology research and therapy” This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.
10 citations
,
November 2018 in “Genetics in medicine” This study identified a genetic variant in the CTS6 gene associated with a hypotrichosis syndrome, emphasizing the significant role of cystatin M/E in hair and skin health.
This study identified compounds like hexadecanoic acid, alphaspinasterol, and squalene in Cucurbita pepo roots, which may offer new pharmacological approaches for developing therapies for various conditions.
99 citations
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May 1998 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that small proline-rich proteins modify the biomechanical properties of cornified cell envelopes in rodent forestomachs, potentially affecting the tissue's ability to withstand mechanical stress.
October 2023 in “Research Square (Research Square)” This study developed a composite product from decellularized human placental connective tissue matrix and placental extract, finding that the combination showed improved biochemical and mechanical properties compared to each component alone, suggesting its potential use for treating chronic and deeper wounds.
182 citations
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August 2016 in “Development” This review discusses the roles and mechanisms of chromatin remodelers and their subunits in mammalian development, but reports no new experimental results.
January 2023 in “Skin appendage disorders” This article describes two cases of plica neuropathica, a rare hair condition involving severe matting, and discusses possible contributing factors and diagnosis methods while reporting no new scientific results.
9 citations
,
August 2021 in “Journal of clinical medicine” This review discusses pili torti, a rare hair shaft disorder, and reports no new clinical results; it emphasizes the need to investigate underlying conditions in affected individuals.
This study reports that carbamazepine can self-assemble into stable channel structures without guest polymers, while griseofulvin relies on guest molecules for structural stability in drug-polymer inclusion complexes.
February 2006 in “Journal of The American Academy of Dermatology” This study found that Malassezia globosa, a scalp-associated fungus linked to dandruff, grows with saturated but not unsaturated fatty acids, potentially causing unsaturated fatty acid accumulation on the scalp and triggering dandruff-like flaking in susceptible individuals.
7 citations
,
December 2020 in “Clinical and Experimental Dermatology” This study found that cepharanthine and its structural analogues may stimulate hair growth by promoting the proliferation of human dermal papilla cells and increasing VEGF expression in vitro.
30 citations
,
April 2017 in “European Journal of Cell Biology” This study observed that CIP/KIP proteins play a significant role in regulating cell cycle arrest and differentiation in human hair follicles, supporting hair growth and formation in the anagen phase.
1 citations
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May 2025 in “Natural Products and Bioprospecting” In this study, PEVIII, a nanocomposite chitosan-coated vesicle containing both α-hederin and hederacoside C, demonstrated notable antibacterial activity against Pseudomonas aeruginosa in a keratitis model, showing significant lesion reduction, tissue improvement, and decreased bacterial load and inflammatory markers compared to other treatments.
18 citations
,
April 2002 in “Journal of cutaneous pathology” This study concludes that tiny infundibular cysts, rather than comedones, are the primary lesions in chloracne.
21 citations
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October 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified specific germline and somatic mutations in the Phospholipase C Delta 1 gene as high-risk factors for developing hereditary trichilemmal cysts, involving a monoallelic two-hit mechanism.
This study found that encapsulating dermal papilla spheroids in alginate hydrogel with extracellular matrix proteins increased alkaline phosphatase activity, suggesting an enhanced manipulation of dermal papilla activity.
21 citations
,
October 1980 in “Gastroenterology” This report is the first to associate Cronkhite-Canada syndrome with multiple myeloma, describing regenerative pseudopolyps in a 58-year-old woman rather than true adenomatous polyps.
83 citations
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May 2011 in “European Journal of Dermatology” This review discusses the role of corneodesmosin in skin and hair follicle integrity, with mentions of its link to hypotrichosis simplex and peeling skin disease, and reports no new results.
27 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article explores the endocrine functions involved in the pathogenesis of polycystic ovarian syndrome and discusses approaches for diagnosing and managing the condition, with no new clinical results reported.
7 citations
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March 2020 in “PloS one” This study demonstrates that α-parvin is crucial for epidermal morphogenesis and hair follicle development by mediating integrin-dependent adhesion and actin organization in keratinocytes.