Cronkhite-Canada Syndrome: Report of an Unusual Case

    October 1980 in “ Gastroenterology ”
    Mary Rubin, Ralph J. Tuthill, Ernest F. Rosato, Seymour S. Cohen
    Image of study
    TLDR The report described a unique case of Cronkhite-Canada syndrome with unusual polyps and an association with multiple myeloma.
    In 1980, a case report described the 18th instance of Cronkhite-Canada syndrome (CCS), a rare condition, in a 58-year-old female. This case was significant for being the first to associate CCS with multiple myeloma and for identifying regenerative pseudopolyps in the patient, rather than the adenomatous polyps typically linked to CCS. The patient exhibited typical CCS symptoms, including gastrointestinal polyps, diarrhea, abdominal discomfort, hypoalbuminemia, alopecia, nail atrophy, and pigmentary changes, with extensive involvement of the gastrointestinal tract and no familial history of related conditions. The findings suggested that polypoid changes in CCS might be inflammatory rather than neoplastic, highlighting the need for further research to better understand the syndrome.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 1000+ results

      community Alopecia Areata Question

      in Treatment  2 upvotes 3 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

      community mbp alopecia areata or vitamin deficiency

      in Chat 5 months ago
      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

      community Androgenic alopecia exclusively on the vertex of the scalp

      in Chat  6 upvotes 7 months ago
      A user experienced androgenic alopecia starting at the vertex without frontal hairline recession and is seeking information on this pattern. Another user noted that vertex or diffuse hair loss is common among men.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 9 months ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  65 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

    Similar Research

    5 / 1000+ results