Pili Torti: A Feature of Numerous Congenital and Acquired Conditions

August 2021 in “ Journal of clinical medicine ”

Aleksandra Hoffmann, Anna Waśkiel‐Burnat, Jakub Żółkiewicz, Leszek Blicharz, Adriana Rakowska, Mohamad Goldust, Małgorzata Olszewska, Lidia Rudnicka

pili torti hair shaft disorder Menkes disease Björnstad syndrome alopecia trichoscopic examination microscopic examination

TLDR Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.

Pili torti is a rare hair shaft disorder where the hair is flattened and twisted, leading to increased fragility. It can be inherited, either alone or as part of genetic syndromes like Menkes disease and Björnstad syndrome, or acquired, associated with conditions such as alopecia, neoplastic and systemic diseases, and can be induced by certain drugs. Diagnosis is made through trichoscopic or microscopic examination, and it's important to investigate for underlying conditions when pili torti is identified.

View this study on mdpi.com →

Discuss this study in the Community →

Cited in this study

23 / 23 results

research Dermoscopic Features of Lichen Planopilaris in Northern Iran: A Prospective Observational Study

3 citations , August 2019 in “International Journal of Dermatology”

Dermoscopy is useful for diagnosing lichen planopilaris and certain features may relate to disease duration, age, and gender.

research Biallelic HEPHL1 Variants Impair Ferroxidase Activity and Cause an Abnormal Hair Phenotype

24 citations , May 2019 in “PLOS genetics”

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

research EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner

13 citations , May 2019 in “iScience”

EGFR helps control how hair grows and forms without needing p53 protein.

research Alopecia Areata: A Multifactorial Autoimmune Condition

148 citations , March 2019 in “Journal of autoimmunity”

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

research Curling of Hair in Two Female Patients Taking Alitretinoin

6 citations , October 2018 in “Drug safety - case reports”

Alitretinoin may cause irreversible hair curling as a side effect.

research Trichoscopy in Hair Shaft Disorders

36 citations , October 2018 in “Dermatologic Clinics”

Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.

research Cicatricial Alopecia: Overview and Treatment Recommendations

23 citations , April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft”

Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.

research Trichoscopy of Alopecia Areata: An Update

89 citations , March 2018 in “The Journal of Dermatology”

Trichoscopy helps diagnose and monitor alopecia areata by looking at a combination of specific hair and scalp features.

research Central Centrifugal Cicatricial Alopecia: Challenges and Solutions

37 citations , August 2016 in “Clinical, Cosmetic and Investigational Dermatology”

The document concludes that better treatments for CCCA are needed and more research is required to understand its causes related to hairstyling and genetics.

research Validity of Trichoscopy in the Diagnosis of Primary Cicatricial Alopecias

34 citations , April 2016 in “International Journal of Dermatology”

Trichoscopy is a useful method for identifying primary cicatricial alopecias and their specific types.

research Curly Hair Induced by Valproate in Bipolar Disorder

5 citations , February 2016 in “Clinical psychopharmacology and neuroscience/Clinical Psychopharmacology and Neuroscience”

Valproate can cause rare hair curling in some patients.

research Bitemporal Hair Loss Related to Traction Alopecia

7 citations , January 2016 in “Dermatology online journal”

Persistent pulling on hair can cause permanent hair loss.

research Trichoscopic Findings of Hair Loss in Koreans

16 citations , January 2015 in “Annals of Dermatology”

The study found specific hair and scalp patterns for different types of hair loss in Koreans, noting racial differences affect diagnosis.

research Clinical Features of Primary Cicatricial Alopecia in Chinese Patients

28 citations , January 2014 in “Indian Journal of Dermatology, Venereology and Leprology”

Chinese patients with primary cicatricial alopecia often have folliculitis decalvans, benefit from treatment, but may experience relapse, with dermoscopy being a useful diagnostic tool.

research Dermatoscopy of Hair Shaft Disorders

68 citations , March 2013 in “Journal of the American Academy of Dermatology”

Dermatoscopy is a useful tool for diagnosing hair disorders and can help choose samples for more detailed analysis.

research Inherited Ichthyoses: Generalized Mendelian Disorders of Cornification

81 citations , June 2012 in “European journal of human genetics”

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

research Trichoscopy Update 2011

178 citations , December 2011 in “Journal of Dermatological Case Reports”

Trichoscopy is a useful tool for diagnosing different hair and scalp diseases by their unique visual features.

research Trichoscopy in Genetic Hair Shaft Abnormalities

74 citations , July 2008 in “Journal of Dermatological Case Reports”

Trichoscopy is a quick and easy way to diagnose most genetic hair problems without invasive methods.

research Low Prevalence of Twisted Hair in Anorexia Nervosa

16 citations , July 2005 in “Clinical and Experimental Dermatology”

Twisted hair is rare in severe anorexia nervosa, found in only 2 out of 30 patients.

research Acquired Pili Torti: A Structural Hair Shaft Defect in Anorexia Nervosa

15 citations , March 1996 in “PubMed”

Anorexia nervosa may cause a hair defect called pili torti due to malnutrition and high vitamin A levels.

research Netherton's Syndrome: A Syndrome of Elevated IgE and Characteristic Skin and Hair Findings

124 citations , January 1995 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

Netherton's syndrome is linked to high IgE levels and unique skin and hair symptoms, and may improve with ammonium lactate lotion and allergy management.

research Disorders of Hair Growth: Diagnosis and Treatment

November 1994 in “JAMA”

The book is a detailed guide on hair growth issues and treatments, recommended for specialists and hospital libraries.

research Pili Torti in Association with Citrullinemia

28 citations , January 1985 in “Journal of the American Academy of Dermatology”

A girl with citrullinemia developed pili torti, suggesting a link between the hair condition and the metabolic disorder.

1 / 1 results

research Treating Resistant Cases of Alopecia Universalis

May 2018 in “Journal of cosmetology & trichology”

Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.