Design and Initial Characterization of Fabricated Composite Scaffold dHPCTM-HPE (Decellularized Human Placental Connective Tissue Matrix - Human Placental Extract)
October 2023
in “
Research Square (Research Square)
”
TLDR The new composite scaffold may effectively treat chronic and deep wounds.
The study developed a composite scaffold, dHPCTM-HPE, by combining decellularized human placental connective tissue matrix and human placental extract in a 1:1 ratio. This composite was created using homogenization, mechanical and chemical treatments, and freeze-drying. The dHPCTM-HPE demonstrated superior biochemical and mechanical properties compared to its individual components, suggesting its potential effectiveness in treating chronic and deep wounds where single interventions may not be sufficient.
