Design and Initial Characterization of Fabricated Composite Scaffold dHPCTM-HPE (Decellularized Human Placental Connective Tissue Matrix - Human Placental Extract)

    October 2023 in “ Research Square (Research Square)
    Prathap Ganesh P C, Mayur Abhaya, Pallavi Misra, Meshack Santhosh Kumar J, M Guruvigneshwari, Joel Israel Daniel B
    TLDR The new composite scaffold may effectively treat chronic and deep wounds.
    The study developed a composite scaffold, dHPCTM-HPE, by combining decellularized human placental connective tissue matrix and human placental extract in a 1:1 ratio. This composite was created using homogenization, mechanical and chemical treatments, and freeze-drying. The dHPCTM-HPE demonstrated superior biochemical and mechanical properties compared to its individual components, suggesting its potential effectiveness in treating chronic and deep wounds where single interventions may not be sufficient.
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