research Antigen-Specific Regulatory T Cells and Low Dose of IL-2 in Treatment of Type 1 Diabetes
Using low-dose IL-2 to increase regulatory T cells might be a safe way to treat type 1 diabetes without severe side effects.
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930-960 / 1000+ resultsresearch Advances in Molecular Pathogenesis of Hidradenitis Suppurativa: Dysregulated Keratins and ECM Signaling
Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
research Effects of the PI3K/Akt Signaling Pathway on the Hair Inductivity of Human Dermal Papilla Cells in Hair Beads
Activating the PI3K/Akt pathway improves hair growth by human dermal papilla cells in hair beads.
research LncRNA RP11-818024.3 Promotes Hair-Follicle Recovery Via FGF2-PI3K/Akt Signal Pathway
LncRNA RP11-818024.3 helps hair growth and recovery in hair loss by boosting cell survival and reducing cell death.
research PDGFA Regulation of Dermal Adipocyte Stem Cells
PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.
research Proteomic Analysis of Fetal Skin by iTRAQ Reveals Molecular Signals Underlying Inner Mongolia Cashmere Goat Hair Follicle Initiation
The research identified proteins that change as goat hair follicles begin to form, helping to understand how cashmere grows.
research Qu-Shi-Yu-Fa Decoction Promotes Hair Cycle and Keratinization by Upregulating Foxn1 and Tgm3 to Treat Androgenetic Alopecia
Qu-shi-yu-fa Decoction may help treat hair loss by promoting hair growth and strengthening hair follicles.
research Elf5, A Novel Regulator of Skin Stem/Progenitor Cells Fate During Skin Development
Elf5 is important for skin stem cell growth and could help treat skin and hair problems.
research Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Capra Hircus
Melatonin affects specific gene patterns and biological processes in goat hair growth.
research In Vitro Co-Culture Models of Merkel Cell-Neurite Complex in Touch Domes
The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
research Adipocyte Stem Cells Are Maintained by PDGFα Signaling in the Skin
Pdgfα signaling helps maintain fat cells in the skin and is important for hair growth, wound healing, and fighting infections.
research Ar/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia
The Ar/miR-221/IGF-1 pathway is involved in male pattern baldness, with miR-221 potentially being a new target for treatment.
research Rational Design of Human Hair Keratin-Driven Proteins for Hair Growth Promotion
RK81 can help promote hair growth.
research Human FOXN1 Deficiency Is Associated with Alpha Beta Double-Negative and FoxP3 Positive T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation
Thymic transplantation normalized some T-cells but not others, maintaining immune function.
research Whole Genome Scan and Selection Signatures for Climate Adaptation in Yanbian Cattle
The CORT, FGF5, and CD36 genes are crucial for the cold weather adaptation of Yanbian cattle.
research Oriental Herbal Medicine and Moxibustion for Polycystic Ovary Syndrome
Oriental herbal medicine with moxibustion may improve pregnancy rates and other symptoms in PCOS, but more high-quality research is needed.
research Human Macrophages Preferentially Infiltrate the Superficial Adipose Tissue
Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
research ADM Scaffolds Generate a Pro-Regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1
ADM scaffolds help skin heal by promoting a healing-type immune response.
research Implication of Human Bacterial Gut Microbiota on Immune-Mediated and Autoimmune Dermatological Diseases and Their Comorbidities: A Narrative Review
An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.
research Acne: Diet and Acnegenesis
Eating dairy and high glycemic foods may increase the risk of acne.
research Association of Gly972Arg Variant of Insulin Receptor Substrate-1 and Gly1057Asp Variant of Insulin Receptor Substrate-2 with Polycystic Ovary Syndrome in the Chinese Population
The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.
research Enrichment and Characterization of Human Dermal Stem/Progenitor Cells by Intracellular Granularity
Scientists identified a unique type of human skin stem cell that could help with tissue repair.
research Functionally Distinct Melanocyte Populations Revealed by Reconstitution of Hair Follicles in Mice
Only skin melanocytes, not other types, can color hair in mice.
research CircRNA-0100 Positively Regulates the Differentiation of Cashmere Goat SHF-SCs into Hair Follicle Lineage via Sequestering miR-153-3p to Heighten the KLF5 Expression
A circular RNA helps cashmere goat hair cells become hair follicles by blocking a molecule to boost a gene important for hair growth.
research The Potential of a Hair Follicle Mesenchymal Stem Cell-Conditioned Medium for Wound Healing and Hair Follicle Regeneration
Hair growth medium helps heal wounds and regrow hair in mice.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research In Silico Analysis of the Age-Dependent Evolution of the Transcriptome of Mouse Skin Stem Cells
The research found that the gene activity in mouse skin stem cells changes significantly as they age.
research Evaluation of Serum Level of Omentin-1 in Females with Hirsutism
Women with hirsutism have different levels of omentin-1, which may be linked to the condition and its genetic aspects.
research Enhanced Restoration of In Situ-Damaged Hairs by Intradermal Transplantation of Trichogenous Dermal Cells
Transplanting a mix of specific skin cells can significantly improve the repair of damaged hair follicles.
research New Drug Targets and Research Methods for Androgenetic Alopecia
The document concludes that more research is needed to create specific drugs for treating male pattern baldness.